OBJECTIVES: The aim of the present study was to evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) in exfoliated buccal mucosa cells from individuals following radiography. METHODS: Lateral and frontal cephalometric X-ray and panoramic dental X-rays were taken of a total of 18 healthy patients (6 male and 12 female) referred for orthodontic therapy. Exfoliated oral mucosa cells were collected immediately before X-ray exposure and after 10 days. RESULTS: The results revealed no statistically significant difference (P > 0.05) in the frequency micronucleated oral mucosa cells after X-ray exposure. However, X-ray was able to increase other nuclear alterations closely related to cytotoxicity, such as karyorrhexis, pyknosis and karyolysis. CONCLUSIONS: Data indicated that exposure to certain radiography may not be a factor in inducing chromosomal damage, but it does promote cytotoxicity.
OBJECTIVES: The aim of the present study was to evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) in exfoliated buccal mucosa cells from individuals following radiography. METHODS: Lateral and frontal cephalometric X-ray and panoramic dental X-rays were taken of a total of 18 healthy patients (6 male and 12 female) referred for orthodontic therapy. Exfoliated oral mucosa cells were collected immediately before X-ray exposure and after 10 days. RESULTS: The results revealed no statistically significant difference (P > 0.05) in the frequency micronucleated oral mucosa cells after X-ray exposure. However, X-ray was able to increase other nuclear alterations closely related to cytotoxicity, such as karyorrhexis, pyknosis and karyolysis. CONCLUSIONS: Data indicated that exposure to certain radiography may not be a factor in inducing chromosomal damage, but it does promote cytotoxicity.
Authors: E M M Cerqueira; I S Gomes-Filho; S Trindade; M A Lopes; J S Passos; G M Machado-Santelli Journal: Mutat Res Date: 2004-08-08 Impact factor: 2.433
Authors: Juliana Bm da Fonte; Taís M de Andrade; Ricardo Lc Albuquerque; Maria de Fátima B de Melo; Wilton M Takeshita Journal: Dentomaxillofac Radiol Date: 2017-11-13 Impact factor: 2.419
Authors: Marcos Antônio Lima Dos Santos; Graziane Ribeiro Couto; Mark Jon Santana Sabey; Danilo de Paula Ribeiro Borges; Wilton Mitsunari Takeshita Journal: Dentomaxillofac Radiol Date: 2021-07-28 Impact factor: 2.419
Authors: Evelyn Louise Antonio; Aguinaldo José do Nascimento; Antonio Adilson Soares de Lima; Maria Suely Soares Leonart; Ângela Fernandes Journal: Rev Paul Pediatr Date: 2017-07-20