Literature DB >> 20840104

Keratoprosthesis with retrocorneal fixation: preliminary results in dogs with corneal blindness.

Pierre-François Isard1, Thomas Dulaurent, Alain Regnier.   

Abstract

OBJECTIVE: To evaluate the use and complications of a penetrating keratoprosthesis implantation in the management of corneal opacification in dogs.
METHODS: A retrospective clinical study describes the indications for the surgical technique utilized and the outcomes of this procedure in 20 eyes of 19 dogs with blindness of corneal origin. A successful surgical outcome was defined as a clear keratoprosthesis optic and improvement or restoration of functional vision over a follow-up period ranging from at least 8 months to a maximum of 7 years.
RESULTS: Eyes with total corneal opacification resulting from chronic superficial keratitis (n = 11), keratoconjunctivitis sicca (n = 5), endothelial dystrophy (n = 3) and chemical burn (n = 1) were treated by unilateral (n = 18) or bilateral (n = 1) full-thickness implantation of a keratoprosthesis. Keratoprostheses were retained in 15 eyes (75%) which regained vision to the date of reporting. Among these eyes, six had uncomplicated postoperative course, five developed retroprosthetic membranes and four developed granulation tissue over the optic of the keratoprostheses. These complications were successfully removed surgically in the nine eyes. The five remaining eyes (25%) developed serious early postoperative complications, for which enucleation had to be performed.
CONCLUSION: In keratopathies in which the corneal opacification could not be treated by standard medical or surgical procedures, this keratoprosthesis appears to be promising to restore vision in chronic superficial keratitis and deep corneal dystrophy. It appears to have a poor prognosis in keratoconjunctivitis sicca in brachycephalic dogs. The post operative complications retro-prosthetic membranes and granulomatous overgrowth could be treated well.

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Year:  2010        PMID: 20840104     DOI: 10.1111/j.1463-5224.2010.00800.x

Source DB:  PubMed          Journal:  Vet Ophthalmol        ISSN: 1463-5216            Impact factor:   1.644


  2 in total

1.  Phenotypic Characterization of Corneal Endothelial Dystrophy in German Shorthaired and Wirehaired Pointers Using In Vivo Advanced Corneal Imaging and Histopathology.

Authors:  Olivia R Shull; Christopher M Reilly; Lola B Davis; Christopher J Murphy; Sara M Thomasy
Journal:  Cornea       Date:  2018-01       Impact factor: 2.651

2.  Evaluation of stability and biocompatibility of PHEMA-PMMA keratoprosthesis by penetrating keratoplasty in rabbits.

Authors:  Yawon Hwang; Gonhyung Kim
Journal:  Lab Anim Res       Date:  2016-12-23
  2 in total

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