Literature DB >> 20840077

Targeting karyotypic complexity and chromosomal instability of cancer cells.

Anna V Roschke1, Ilan R Kirsch.   

Abstract

Multiple karyotypic abnormalities and chromosomal instability are characteristic features of many cancers that are relatively resistant to chemotherapeutic agents currently used in the clinic. These same features represent potentially targetable "states" that are essentially tumor specific. The assessment of the chromosomal state of a cancer cell population may provide a guide for the selection or development of drugs active against aggressive and intractable cancers.

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Year:  2010        PMID： 20840077      PMCID： PMC3309604          DOI： 10.2174/1389450111007011341

Source DB:  PubMed          Journal:  Curr Drug Targets        ISSN： 1389-4501            Impact factor:   3.465


  100 in total

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Authors:  Jie-Guang Chen; Susan Band Horwitz
Journal:  Cancer Res       Date:  2002-04-01       Impact factor: 12.701

2.  Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E.

Authors:  Frances R Putkey; Thorsten Cramer; Mary K Morphew; Alain D Silk; Randall S Johnson; J Richard McIntosh; Don W Cleveland
Journal:  Dev Cell       Date:  2002-09       Impact factor: 12.270

3.  Insights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalator.

Authors:  Valérie C Pierre; Jens T Kaiser; Jacqueline K Barton
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-28       Impact factor: 11.205

4.  Effect of cytochalasin B and cycloheximide on the activation rate, chromosome constituent and in vitro development of porcine oocytes following parthenogenetic stimulation.

Authors:  S K Cha; N H Kim; S M Lee; C S Baik; H T Lee; K S Chung
Journal:  Reprod Fertil Dev       Date:  1997       Impact factor: 2.311

5.  Karyotypic "state" as a potential determinant for anticancer drug discovery.

Authors:  Anna V Roschke; Samir Lababidi; Giovanni Tonon; Kristen S Gehlhaus; Kimberly Bussey; John N Weinstein; Ilan R Kirsch
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-09       Impact factor: 11.205

Review 6.  Genomic mechanisms and measurement of structural and numerical instability in cancer cells.

Authors:  Jane Bayani; Shamini Selvarajah; Georges Maire; Bisera Vukovic; Khaldoun Al-Romaih; Maria Zielenska; Jeremy A Squire
Journal:  Semin Cancer Biol       Date:  2006-10-26       Impact factor: 15.707

7.  Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities.

Authors:  Alfred A Rabow; Robert H Shoemaker; Edward A Sausville; David G Covell
Journal:  J Med Chem       Date:  2002-02-14       Impact factor: 7.446

8.  Genome-wide analysis of DNA copy number alterations and gene expression in gastric cancer.

Authors:  Y Tsukamoto; T Uchida; S Karnan; T Noguchi; L T Nguyen; M Tanigawa; I Takeuchi; K Matsuura; N Hijiya; C Nakada; T Kishida; K Kawahara; H Ito; K Murakami; T Fujioka; M Seto; M Moriyama
Journal:  J Pathol       Date:  2008-12       Impact factor: 7.996

9.  Genome stability is ensured by temporal control of kinetochore-microtubule dynamics.

Authors:  Samuel F Bakhoum; Sarah L Thompson; Amity L Manning; Duane A Compton
Journal:  Nat Cell Biol       Date:  2008-12-07       Impact factor: 28.824

10.  Mitosis in a cell with multiple centrioles.

Authors:  D Ring; R Hubble; M Kirschner
Journal:  J Cell Biol       Date:  1982-09       Impact factor: 10.539
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  15 in total

Review 1.  Cancer chromosomal instability: therapeutic and diagnostic challenges.

Authors:  Nicholas McGranahan; Rebecca A Burrell; David Endesfelder; Marco R Novelli; Charles Swanton
Journal:  EMBO Rep       Date:  2012-06-01       Impact factor: 8.807

2.  Alternative lengthening of telomeres: recurrent cytogenetic aberrations and chromosome stability under extreme telomere dysfunction.

Authors:  Despoina Sakellariou; Maria Chiourea; Christina Raftopoulou; Sarantis Gagos
Journal:  Neoplasia       Date:  2013-11       Impact factor: 5.715

Review 3.  pRB, a tumor suppressor with a stabilizing presence.

Authors:  Amity L Manning; Nicholas J Dyson
Journal:  Trends Cell Biol       Date:  2011-06-12       Impact factor: 20.808

4.  Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines.

Authors:  Geula Klorin; Ester Rozenblum; Oleg Glebov; Robert L Walker; Yoonsoo Park; Paul S Meltzer; Ilan R Kirsch; Frederic J Kaye; Anna V Roschke
Journal:  Cancer Genet       Date:  2013-07-05

5.  Genomic Instability and Cancer.

Authors:  Yixin Yao; Wei Dai
Journal:  J Carcinog Mutagen       Date:  2014

6.  Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability.

Authors:  Yurong Song; Shaneen S Baxter; Lisheng Dai; Chelsea Sanders; Sandra Burkett; Ryan N Baugher; Stephanie D Mellott; Todd B Young; Heidi E Lawhorn; Simone Difilippantonio; Baktiar Karim; Yuwaraj Kadariya; Ligia A Pinto; Joseph R Testa; Robert H Shoemaker
Journal:  Cancers (Basel)       Date:  2022-06-24       Impact factor: 6.575

Review 7.  Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.

Authors:  Marco Raffaele Cosenza; Alwin Krämer
Journal:  Chromosome Res       Date:  2016-01       Impact factor: 5.239

Review 8.  Losing balance: the origin and impact of aneuploidy in cancer.

Authors:  Andrew J Holland; Don W Cleveland
Journal:  EMBO Rep       Date:  2012-06-01       Impact factor: 8.807

9.  A Selective β-Catenin-Metadherin/CEACAM1-CCL3 Axis Mediates Metastatic Heterogeneity upon Tumor-Macrophage Interaction.

Authors:  Sally K Y To; Maggie K S Tang; Yin Tong; Jiangwen Zhang; Karen K L Chan; Philip P C Ip; Jue Shi; Alice S T Wong
Journal:  Adv Sci (Weinh)       Date:  2022-04-11       Impact factor: 17.521

Review 10.  Taxane benefit in breast cancer--a role for grade and chromosomal stability.

Authors:  Roger P A'Hern; Mariam Jamal-Hanjani; A Marcell Szász; Stephen R D Johnston; Jorge S Reis-Filho; Rebecca Roylance; Charles Swanton
Journal:  Nat Rev Clin Oncol       Date:  2013-05-07       Impact factor: 66.675
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