Literature DB >> 20836523

A short synthesis of the triazolopyrimidine antibiotic essramycin.

Ugo Battaglia1, Christopher J Moody.   

Abstract

A short synthesis of the 1,2,4-triazolo[1,5-a]pyrimidine antibiotic essramycin is described involving condensation of aminoguanidine with ethyl benzoylacetate to give an amino-1,2,4-triazole, followed by condensation with ethyl acetoacetate to form the pyrimidone ring.

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Year:  2010        PMID: 20836523     DOI: 10.1021/np100298m

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  4 in total

1.  The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity.

Authors:  Huan Wang; Dusan Hesek; Mijoon Lee; Elena Lastochkin; Allen G Oliver; Mayland Chang; Shahriar Mobashery
Journal:  J Nat Prod       Date:  2016-04-06       Impact factor: 4.050

2.  A Short and Efficient Total Synthesis of Ficuseptamines A and B.

Authors:  Hani Mutlak A Hassan
Journal:  Molecules       Date:  2018-07-26       Impact factor: 4.411

3.  Retracted Article: The synthesis and biological activity of marine alkaloid derivatives and analogues.

Authors:  Shiyang Zhou; Gangliang Huang
Journal:  RSC Adv       Date:  2020-08-28       Impact factor: 4.036

4.  IBD-mediated oxidative cyclization of pyrimidinylhydrazones and concurrent Dimroth rearrangement: Synthesis of [1,2,4]triazolo[1,5-c]pyrimidine derivatives.

Authors:  Caifei Tang; Zhiming Li; Quanrui Wang
Journal:  Beilstein J Org Chem       Date:  2013-11-25       Impact factor: 2.883

  4 in total

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