Literature DB >> 20835451

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.

Mathieu Galibert1, Lucie Sancey, Olivier Renaudet, Jean-Luc Coll, Pascal Dumy, Didier Boturyn.   

Abstract

New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.

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Year:  2010        PMID: 20835451      PMCID: PMC4823385          DOI: 10.1039/c0ob00070a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  41 in total

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Review 3.  Bioorthogonal chemistry: recent progress and future directions.

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4.  Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells.

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Journal:  Org Biomol Chem       Date:  2008-11-17       Impact factor: 3.876

5.  Dual labeling of biomolecules by using click chemistry: a sequential approach.

Authors:  Péter Kele; Gábor Mezö; Daniela Achatz; Otto S Wolfbeis
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6.  Synthesis and biological characterisation of targeted pro-apoptotic peptide.

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7.  Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands.

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8.  Anti-cancer activity of targeted pro-apoptotic peptides.

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9.  Combined Cu(I)-catalysed alkyne-azide cycloaddition and furan-maleimide Diels-Alder "click" chemistry approach to thermoresponsive dendrimers.

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10.  In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)(4).

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  6 in total

1.  Advantages of RGD peptides for directing cell association with biomaterials.

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Journal:  Biomaterials       Date:  2011-06       Impact factor: 12.479

2.  Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression.

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Journal:  Mol Pharm       Date:  2011-11-15       Impact factor: 4.939

3.  (99m)Tc-Galacto-RGD2: a novel 99mTc-labeled cyclic RGD peptide dimer useful for tumor imaging.

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4.  Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds.

Authors:  Ethan A Englund; Deyun Wang; Hidetsugu Fujigaki; Hiroyasu Sakai; Christopher M Micklitsch; Rodolfo Ghirlando; Gema Martin-Manso; Michael L Pendrak; David D Roberts; Stewart R Durell; Daniel H Appella
Journal:  Nat Commun       Date:  2012-01-10       Impact factor: 14.919

5.  Multifunctional Glycoconjugates for Recruiting Natural Antibodies against Cancer Cells.

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Journal:  Chemistry       Date:  2019-10-15       Impact factor: 5.236

6.  Cathepsin B-Cleavable Cyclopeptidic Chemotherapeutic Prodrugs.

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Journal:  Molecules       Date:  2020-09-18       Impact factor: 4.411

  6 in total

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