Literature DB >> 20829829

A holistic view of GPCR signaling.

Terry Kenakin.   

Abstract

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Year:  2010        PMID： 20829829     DOI： 10.1038/nbt0910-928

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  8 in total

1.  A modification of receptor theory.

Authors:  R P STEPHENSON
Journal:  Br J Pharmacol Chemother       Date:  1956-12

2.  Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements.

Authors:  Ralf Schröder; Nicole Janssen; Johannes Schmidt; Anna Kebig; Nicole Merten; Stephanie Hennen; Anke Müller; Stefanie Blättermann; Marion Mohr-Andrä; Sabine Zahn; Jörg Wenzel; Nicola J Smith; Jesús Gomeza; Christel Drewke; Graeme Milligan; Klaus Mohr; Evi Kostenis
Journal:  Nat Biotechnol       Date:  2010-08-15       Impact factor: 54.908

Review 3.  Beyond desensitization: physiological relevance of arrestin-dependent signaling.

Authors:  Louis M Luttrell; Diane Gesty-Palmer
Journal:  Pharmacol Rev       Date:  2010-04-28       Impact factor: 25.468

Review 4.  Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.

Authors:  Terry Kenakin; Laurence J Miller
Journal:  Pharmacol Rev       Date:  2010-04-14       Impact factor: 25.468

Review 5.  Beta-arrestin-biased ligands at seven-transmembrane receptors.

Authors:  Jonathan D Violin; Robert J Lefkowitz
Journal:  Trends Pharmacol Sci       Date:  2007-07-20       Impact factor: 14.819

6.  Evaluating cellular impedance assays for detection of GPCR pleiotropic signaling and functional selectivity.

Authors:  Matthew F Peters; Clay W Scott
Journal:  J Biomol Screen       Date:  2009-02-11

7.  Operational models of pharmacological agonism.

Authors:  J W Black; P Leff
Journal:  Proc R Soc Lond B Biol Sci       Date:  1983-12-22

Review 8.  Agonist-receptor efficacy. II. Agonist trafficking of receptor signals.

Authors:  T Kenakin
Journal:  Trends Pharmacol Sci       Date:  1995-07       Impact factor: 14.819
  8 in total
  10 in total

Review 1.  The significance of G protein-coupled receptor crystallography for drug discovery.

Authors:  John A Salon; David T Lodowski; Krzysztof Palczewski
Journal:  Pharmacol Rev       Date:  2011-12       Impact factor: 25.468

2.  Rendomab B4, a monoclonal antibody that discriminates the human endothelin B receptor of melanoma cells and inhibits their migration.

Authors:  Aurélie Borrull; Bertrand Allard; Anne Wijkhuisen; Amaury Herbet; Patricia Lamourette; Wided Birouk; Denis Leiber; Zahra Tanfin; Frédéric Ducancel; Didier Boquet; Jean-Yves Couraud; Philippe Robin
Journal:  MAbs       Date:  2016-07-08       Impact factor: 5.857

3.  Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.

Authors:  Ralf Schröder; Johannes Schmidt; Stefanie Blättermann; Lucas Peters; Nicole Janssen; Manuel Grundmann; Wiebke Seemann; Dorina Kaufel; Nicole Merten; Christel Drewke; Jesus Gomeza; Graeme Milligan; Klaus Mohr; Evi Kostenis
Journal:  Nat Protoc       Date:  2011-10-20       Impact factor: 13.491

Review 4.  Approaches for probing allosteric interactions at 7 transmembrane spanning receptors.

Authors:  Michael T Klein; Paige N Vinson; Colleen M Niswender
Journal:  Prog Mol Biol Transl Sci       Date:  2013       Impact factor: 3.622

5.  5-HT1A receptor pharmacophores to screen for off-target activity of α1-adrenoceptor antagonists.

Authors:  Tony Ngo; Timothy J Nicholas; Junli Chen; Angela M Finch; Renate Griffith
Journal:  J Comput Aided Mol Des       Date:  2013-04-27       Impact factor: 3.686

6.  Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors.

Authors:  Xiao-Feng Xiong; Hang Zhang; Christina R Underwood; Kasper Harpsøe; Thomas J Gardella; Mie F Wöldike; Michael Mannstadt; David E Gloriam; Hans Bräuner-Osborne; Kristian Strømgaard
Journal:  Nat Chem       Date:  2016-07-25       Impact factor: 24.427

7.  Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40.

Authors:  Johannes Schmidt; Kathrin Liebscher; Nicole Merten; Manuel Grundmann; Manfred Mielenz; Helga Sauerwein; Elisabeth Christiansen; Maria E Due-Hansen; Trond Ulven; Susanne Ullrich; Jesús Gomeza; Christel Drewke; Evi Kostenis
Journal:  J Biol Chem       Date:  2011-02-21       Impact factor: 5.157

8.  Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.

Authors:  Johannes Schmidt; Nicola J Smith; Elisabeth Christiansen; Irina G Tikhonova; Manuel Grundmann; Brian D Hudson; Richard J Ward; Christel Drewke; Graeme Milligan; Evi Kostenis; Trond Ulven
Journal:  J Biol Chem       Date:  2011-01-10       Impact factor: 5.157

9.  A Dynamic Mass Redistribution Assay for the Human Sweet Taste Receptor Uncovers G-Protein Dependent Biased Ligands.

Authors:  Nicole B Servant; Mark E Williams; Paul F Brust; Huixian Tang; Melissa S Wong; Qing Chen; Marketa Lebl-Rinnova; Sara L Adamski-Werner; Catherine Tachdjian; Guy Servant
Journal:  Front Pharmacol       Date:  2022-02-17       Impact factor: 5.810

10.  Methamphetamine Blocks Adenosine A2A Receptor Activation via Sigma 1 and Cannabinoid CB1 Receptors.

Authors:  Mireia Casanovas; Irene Reyes-Resina; Alejandro Lillo; Jaume Lillo; Raul López-Arnau; Jorge Camarasa; Elena Escubedo; Gemma Navarro; Rafael Franco
Journal:  Int J Mol Sci       Date:  2021-03-09       Impact factor: 5.923
  10 in total

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