Literature DB >> 20829112

Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection.

Michelle L Janas1, Martin Turner.   

Abstract

The progressive maturation of T cells is accompanied by their migration through the thymus, with each selection stage occurring in distinct microenvironments. Many specialized receptor-ligand pairs have been defined that drive T cell differentiation, but our understanding of the complex relationship between T cells and the thymic stroma is incomplete. Recent reports have identified a role for the chemokine stromal cell-derived factor 1α and its receptor CXC chemokine receptor 4 in β-selection. This review explores these findings in detail.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20829112     DOI： 10.1016/j.it.2010.07.002

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  14 in total

1.  Single and coexpression of CXCR4 and CXCR5 identifies CD4 T helper cells in distinct lymph node niches during influenza virus infection.

Authors:  Rebecca A Elsner; David N Ernst; Nicole Baumgarth
Journal:  J Virol       Date:  2012-04-24       Impact factor: 5.103

2.  Plerixafor for the Treatment of WHIM Syndrome.

Authors:  David H McDermott; Diana V Pastrana; Katherine R Calvo; Stefania Pittaluga; Daniel Velez; Elena Cho; Qian Liu; Hugh H Trout; João F Neves; Pamela J Gardner; David A Bianchi; Elizabeth A Blair; Emily M Landon; Susana L Silva; Christopher B Buck; Philip M Murphy
Journal:  N Engl J Med       Date:  2019-01-10       Impact factor: 91.245

Review 3.  How to find your way through the thymus: a practical guide for aspiring T cells.

Authors:  Ivan Dzhagalov; Hyewon Phee
Journal:  Cell Mol Life Sci       Date:  2011-08-14       Impact factor: 9.261

4.  Aquaporin-3 Controls Breast Cancer Cell Migration by Regulating Hydrogen Peroxide Transport and Its Downstream Cell Signaling.

Authors:  Hiroki Satooka; Mariko Hara-Chikuma
Journal:  Mol Cell Biol       Date:  2016-02-01       Impact factor: 4.272

5.  Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice.

Authors:  Christian Reimann; Emmanuelle Six; Liliane Dal-Cortivo; Andrea Schiavo; Kevin Appourchaux; Chantal Lagresle-Peyrou; Corinne de Chappedelaine; Brigitte Ternaux; Laure Coulombel; Kheira Beldjord; Marina Cavazzana-Calvo; Isabelle Andre-Schmutz
Journal:  Stem Cells       Date:  2012-08       Impact factor: 6.277

Review 6.  Signaling by the phosphoinositide 3-kinase family in immune cells.

Authors:  Klaus Okkenhaug
Journal:  Annu Rev Immunol       Date:  2013-01-16       Impact factor: 28.527

7.  RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.

Authors:  Dominic P Golec; Nancy A Dower; James C Stone; Troy A Baldwin
Journal:  PLoS One       Date:  2013-01-07       Impact factor: 3.240

8.  Pharmacological inhibition of glycogen synthase kinase 3 regulates T cell development in vitro.

Authors:  Jan-Hendrik Schroeder; Lewis S Bell; Michelle L Janas; Martin Turner
Journal:  PLoS One       Date:  2013-03-20       Impact factor: 3.240

9.  Gene expression profiling in peripheral blood mononuclear cells of patients with common variable immunodeficiency: modulation of adaptive immune response following intravenous immunoglobulin therapy.

Authors:  Marzia Dolcino; Giuseppe Patuzzo; Alessandro Barbieri; Elisa Tinazzi; Monica Rizzi; Ruggero Beri; Giuseppe Argentino; Andrea Ottria; Claudio Lunardi; Antonio Puccetti
Journal:  PLoS One       Date:  2014-05-15       Impact factor: 3.240

10.  The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression.

Authors:  Katharina U Vogel; Lewis S Bell; Alison Galloway; Helena Ahlfors; Martin Turner
Journal:  J Immunol       Date:  2016-08-26       Impact factor: 5.422
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