| Literature DB >> 20827317 |
Xiaodong Ma, Tim Wu, Michael P Robich, Xingwei Wang, Hao Wu, Bryan Buchholz, Stephen McCarthy.
Abstract
Coronary artery disease (CAD) is currently a leading cause of death worldwide. Drug-eluting stents (DESs) have been dominant for the treatment of CAD in the interventional cardiology world owing to their efficacy in significantly reducing restenosis. However, late stage stent thrombosis has become a major concern. Stent platform, drug delivery vehicle and type of drug are three parts of DES and each part affects the performance of the DES. Aiming to provide a clue for the design of future DES, this review focuses on the development of the three major components of DES and their roles in restenosis and thrombosis.Entities:
Keywords: Drug-eluting stents; restenosis; thrombosis
Year: 2010 PMID: 20827317 PMCID: PMC2929945
Source DB: PubMed Journal: Int J Clin Exp Med ISSN: 1940-5901