Literature DB >> 20826478

Regenerative nanomedicines: an emerging investment prospective?

Catherine Prescott1.   

Abstract

Cells respond to their structural surrounding and within nanostructures exhibit unique proliferative and differentiation properties. The application of nanotechnologies to the field of regenerative medicine offers the potential to direct cell fate, target the delivery of cells and reduce immune rejection (via encapsulation), thereby supporting the development of regenerative medicines. The overall objective of any therapy is the delivery of the product not just into the clinic but also to patients on a routine basis. Such a goal typically requires a commercial vehicle and substantial levels of investment in scientific, clinical, regulatory and business expertise, resources, time and funding. Therefore, this paper focuses on some of the challenges facing this emerging industry, including investment by the venture capital community.

Entities:  

Mesh:

Year:  2010        PMID: 20826478      PMCID: PMC2988278          DOI: 10.1098/rsif.2010.0351.focus

Source DB:  PubMed          Journal:  J R Soc Interface        ISSN: 1742-5662            Impact factor:   4.118


  7 in total

Review 1.  The gatekeepers of hES cell products.

Authors:  Sander Rabin
Journal:  Nat Biotechnol       Date:  2005-07       Impact factor: 54.908

2.  Stem cell fate dictated solely by altered nanotube dimension.

Authors:  Seunghan Oh; Karla S Brammer; Y S Julie Li; Dayu Teng; Adam J Engler; Shu Chien; Sungho Jin
Journal:  Proc Natl Acad Sci U S A       Date:  2009-01-28       Impact factor: 11.205

Review 3.  Controlling biological interfaces on the nanometer length scale.

Authors:  Ray C Schmidt; Kevin E Healy
Journal:  J Biomed Mater Res A       Date:  2009-09-15       Impact factor: 4.396

4.  The gold rush for induced pluripotent stem cells.

Authors:  Sarah Webb
Journal:  Nat Biotechnol       Date:  2009-11       Impact factor: 54.908

Review 5.  Nanostructured polymer scaffolds for tissue engineering and regenerative medicine.

Authors:  I O Smith; X H Liu; L A Smith; P X Ma
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2009 Mar-Apr

6.  In vivo tracking of superparamagnetic iron oxide nanoparticle-labeled mesenchymal stem cell tropism to malignant gliomas using magnetic resonance imaging. Laboratory investigation.

Authors:  Xing Wu; Jin Hu; Liangfu Zhou; Ying Mao; Bojie Yang; Liang Gao; Rong Xie; Feng Xu; Dong Zhang; Jun Liu; Jianhong Zhu
Journal:  J Neurosurg       Date:  2008-02       Impact factor: 5.115

Review 7.  Biomimetic and bioactive nanofibrous scaffolds from electrospun composite nanofibers.

Authors:  Y Z Zhang; B Su; J Venugopal; S Ramakrishna; C T Lim
Journal:  Int J Nanomedicine       Date:  2007
  7 in total
  1 in total

1.  Translation and commercialization of regenerative medicines.

Authors:  Julia Polak; Christopher A Bravery; Catherine Prescott
Journal:  J R Soc Interface       Date:  2010-10-06       Impact factor: 4.118

  1 in total

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