Stijn Soenen1, Guy Plasqui, Astrid J Smeets, Margriet S Westerterp-Plantenga. 1. Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Top Institute Food and Nutrition (TIFN), Maastricht University,P.O. Box 616, 6200 MD Maastricht, The Netherlands. S.Soenen@HB.unimaas.nl
Abstract
BACKGROUND: Protein-rich weight-loss diets spare fat-free mass at the cost of fat mass. The objective was to examine if there is a change in stimulated fat oxidation related to protein intake during stable body weight. METHODS:Subjects' (BMI 22±2kg/m(2), age 25±8 years) maximal fat oxidation (Fat(max)) was assessed during a graded bicycle test, before and after a 3-month dietary-intervention of 2MJ/day supplements exchanged with 2MJ/d of habitual energy intake. The parallel design consisted of protein-rich supplements in the protein group and an isocaloric combination of carbohydrate and fat supplements in the control group. Daily protein intake was determined according to 24-h urine nitrogen. Body composition was measured according to a 4-compartment model by a combination of underwater-weighing technique, deuterium-dilution technique and whole-body dual-energy X-ray absorptiometry (DXA). RESULTS: Subjects were weight stable and did not change their physical activity. The protein group (n=12) increased protein intake (11±14g, P<0.05) and had significantly higher daily protein intake vs. control (n=4) (80±21 vs.59±11g, P<0.05). Fat(max) increased significantly in the protein group (0.08±0.08g/min, P<0.01). Fat-free mass increased independent of change in body weight (P<0.01), and fat mass and fat percentage decreased (P<0.05). Change in Fat(max) was a function of change in protein intake (r=0.623, P<0.05), and not of changes in body composition or VO(2)max. CONCLUSION: Increased stimulated fat oxidation was related to increased protein intake.
RCT Entities:
BACKGROUND: Protein-rich weight-loss diets spare fat-free mass at the cost of fat mass. The objective was to examine if there is a change in stimulated fat oxidation related to protein intake during stable body weight. METHODS: Subjects' (BMI 22±2kg/m(2), age 25±8 years) maximal fat oxidation (Fat(max)) was assessed during a graded bicycle test, before and after a 3-month dietary-intervention of 2MJ/day supplements exchanged with 2MJ/d of habitual energy intake. The parallel design consisted of protein-rich supplements in the protein group and an isocaloric combination of carbohydrate and fat supplements in the control group. Daily protein intake was determined according to 24-h urine nitrogen. Body composition was measured according to a 4-compartment model by a combination of underwater-weighing technique, deuterium-dilution technique and whole-body dual-energy X-ray absorptiometry (DXA). RESULTS: Subjects were weight stable and did not change their physical activity. The protein group (n=12) increased protein intake (11±14g, P<0.05) and had significantly higher daily protein intake vs. control (n=4) (80±21 vs.59±11g, P<0.05). Fat(max) increased significantly in the protein group (0.08±0.08g/min, P<0.01). Fat-free mass increased independent of change in body weight (P<0.01), and fat mass and fat percentage decreased (P<0.05). Change in Fat(max) was a function of change in protein intake (r=0.623, P<0.05), and not of changes in body composition or VO(2)max. CONCLUSION: Increased stimulated fat oxidation was related to increased protein intake.
Authors: Wayne W Campbell; Jung Eun Kim; Akua F Amankwaah; Susannah L Gordon; Eileen M Weinheimer-Haus Journal: J Nutr Date: 2015-08-05 Impact factor: 4.798
Authors: Gareth Fletcher; Frank F Eves; Elisa I Glover; Scott L Robinson; Carlijn A Vernooij; Janice L Thompson; Gareth A Wallis Journal: Am J Clin Nutr Date: 2017-03-01 Impact factor: 7.045