Literature DB >> 20822154

O-silylative Passerini reaction: a new one-pot synthesis of α-siloxyamides.

Takahiro Soeta1, Yuuki Kojima, Yutaka Ukaji, Katsuhiko Inomata.   

Abstract

A new method for the highly effective synthesis of α-siloxyamides is described. The addition of isocyanide to aldehyde proceeded smoothly in the presence of silanol to give the corresponding α-siloxyamides in high yields. A wide range of aldehydes and isocyanides are applicable in this reaction.

Entities:  

Year:  2010        PMID： 20822154     DOI： 10.1021/ol101763w

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides.

Authors:  Ajay L Chandgude; Alexander Dömling
Journal:  Org Lett       Date:  2017-02-21       Impact factor: 6.005

Review 2.  The 100 facets of the Passerini reaction.

Authors:  Luca Banfi; Andrea Basso; Chiara Lambruschini; Lisa Moni; Renata Riva
Journal:  Chem Sci       Date:  2021-09-30       Impact factor: 9.825

Review 3.  Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles.

Authors:  András Váradi; Travis C Palmer; Rebecca Notis Dardashti; Susruta Majumdar
Journal:  Molecules       Date:  2015-12-23       Impact factor: 4.411

4.  Hexafluoroisopropanol as the Acid Component in the Passerini Reaction: One-Pot Access to β-Amino Alcohols.

Authors:  Jordy M Saya; Rayan Berabez; Pim Broersen; Imme Schuringa; Art Kruithof; Romano V A Orru; Eelco Ruijter
Journal:  Org Lett       Date:  2018-06-15       Impact factor: 6.005
  4 in total

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