Literature DB >> 20819859

Extracting Rx information from clinical narrative.

James G Mork1, Olivier Bodenreider, Dina Demner-Fushman, Rezarta Islamaj Dogan, François-Michel Lang, Zhiyong Lu, Aurélie Névéol, Lee Peters, Sonya E Shooshan, Alan R Aronson.   

Abstract

OBJECTIVE: The authors used the i2b2 Medication Extraction Challenge to evaluate their entity extraction methods, contribute to the generation of a publicly available collection of annotated clinical notes, and start developing methods for ontology-based reasoning using structured information generated from the unstructured clinical narrative.
DESIGN: Extraction of salient features of medication orders from the text of de-identified hospital discharge summaries was addressed with a knowledge-based approach using simple rules and lookup lists. The entity recognition tool, MetaMap, was combined with dose, frequency, and duration modules specifically developed for the Challenge as well as a prototype module for reason identification. MEASUREMENTS: Evaluation metrics and corresponding results were provided by the Challenge organizers.
RESULTS: The results indicate that robust rule-based tools achieve satisfactory results in extraction of simple elements of medication orders, but more sophisticated methods are needed for identification of reasons for the orders and durations. LIMITATIONS: Owing to the time constraints and nature of the Challenge, some obvious follow-on analysis has not been completed yet.
CONCLUSIONS: The authors plan to integrate the new modules with MetaMap to enhance its accuracy. This integration effort will provide guidance in retargeting existing tools for better processing of clinical text.

Mesh:

Substances:

Year:  2010        PMID: 20819859      PMCID: PMC2995679          DOI: 10.1136/jamia.2010.003970

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  12 in total

1.  Extracting medication information from clinical text.

Authors:  Ozlem Uzuner; Imre Solti; Eithon Cadag
Journal:  J Am Med Inform Assoc       Date:  2010 Sep-Oct       Impact factor: 4.497

2.  Study of effect of drug lexicons on medication extraction from electronic medical records.

Authors:  E Sirohi; P Peissig
Journal:  Pac Symp Biocomput       Date:  2005

3.  Medication reconciliation using natural language processing and controlled terminologies.

Authors:  James J Cimino; Tiffani J Bright; Jianhua Li
Journal:  Stud Health Technol Inform       Date:  2007

4.  Identification of documented medication non-adherence in physician notes.

Authors:  Alexander Turchin; Holly I Wheeler; Matthew Labreche; Julia T Chu; Merri L Pendergrass; Jonathan S Einbinder; Jonathan Seth Einbinder
Journal:  AMIA Annu Symp Proc       Date:  2008-11-06

5.  Methodology for creating UMLS content views appropriate for biomedical natural language processing.

Authors:  Alan R Aronson; James G Mork; Aurélie Névéol; Sonya E Shooshan; Dina Demner-Fushman
Journal:  AMIA Annu Symp Proc       Date:  2008-11-06

6.  Extracting structured medication event information from discharge summaries.

Authors:  Sigfried Gold; Noémie Elhadad; Xinxin Zhu; James J Cimino; George Hripcsak
Journal:  AMIA Annu Symp Proc       Date:  2008-11-06

7.  MedEx: a medication information extraction system for clinical narratives.

Authors:  Hua Xu; Shane P Stenner; Son Doan; Kevin B Johnson; Lemuel R Waitman; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2010 Jan-Feb       Impact factor: 4.497

8.  Automating concept identification in the electronic medical record: an experiment in extracting dosage information.

Authors:  D A Evans; N D Brownlow; W R Hersh; E M Campbell
Journal:  Proc AMIA Annu Fall Symp       Date:  1996

9.  The Medical Gopher--a microcomputer system to help find, organize and decide about patient data.

Authors:  C J McDonald; W M Tierney
Journal:  West J Med       Date:  1986-12

10.  Identification of inactive medications in narrative medical text.

Authors:  Eugene M Breydo; Julia T Chu; Alexander Turchin
Journal:  AMIA Annu Symp Proc       Date:  2008-11-06
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  16 in total

1.  Comparison of UMLS terminologies to identify risk of heart disease using clinical notes.

Authors:  Chaitanya Shivade; Pranav Malewadkar; Eric Fosler-Lussier; Albert M Lai
Journal:  J Biomed Inform       Date:  2015-09-12       Impact factor: 6.317

2.  Automating annotation of information-giving for analysis of clinical conversation.

Authors:  Elijah Mayfield; M Barton Laws; Ira B Wilson; Carolyn Penstein Rosé
Journal:  J Am Med Inform Assoc       Date:  2013-09-12       Impact factor: 4.497

3.  MedXN: an open source medication extraction and normalization tool for clinical text.

Authors:  Sunghwan Sohn; Cheryl Clark; Scott R Halgrim; Sean P Murphy; Christopher G Chute; Hongfang Liu
Journal:  J Am Med Inform Assoc       Date:  2014-03-17       Impact factor: 4.497

4.  Improving the validity of determining medication adherence from electronic health record medications orders.

Authors:  Nikki M Carroll; Jennifer L Ellis; Capp F Luckett; Marsha A Raebel
Journal:  J Am Med Inform Assoc       Date:  2011-05-25       Impact factor: 4.497

5.  Clinical Informatics Researcher's Desiderata for the Data Content of the Next Generation Electronic Health Record.

Authors:  Timothy I Kennell; James H Willig; James J Cimino
Journal:  Appl Clin Inform       Date:  2017-12-21       Impact factor: 2.342

6.  NCBI disease corpus: a resource for disease name recognition and concept normalization.

Authors:  Rezarta Islamaj Doğan; Robert Leaman; Zhiyong Lu
Journal:  J Biomed Inform       Date:  2014-01-03       Impact factor: 6.317

Review 7.  Natural language processing systems for capturing and standardizing unstructured clinical information: A systematic review.

Authors:  Kory Kreimeyer; Matthew Foster; Abhishek Pandey; Nina Arya; Gwendolyn Halford; Sandra F Jones; Richard Forshee; Mark Walderhaug; Taxiarchis Botsis
Journal:  J Biomed Inform       Date:  2017-07-17       Impact factor: 6.317

Review 8.  Clinical concept extraction: A methodology review.

Authors:  Sunyang Fu; David Chen; Huan He; Sijia Liu; Sungrim Moon; Kevin J Peterson; Feichen Shen; Liwei Wang; Yanshan Wang; Andrew Wen; Yiqing Zhao; Sunghwan Sohn; Hongfang Liu
Journal:  J Biomed Inform       Date:  2020-08-06       Impact factor: 6.317

9.  A cascade of classifiers for extracting medication information from discharge summaries.

Authors:  Scott Russell Halgrim; Fei Xia; Imre Solti; Eithon Cadag; Ozlem Uzuner
Journal:  J Biomed Semantics       Date:  2011-07-14

10.  Using nanoinformatics methods for automatically identifying relevant nanotoxicology entities from the literature.

Authors:  Miguel García-Remesal; Alejandro García-Ruiz; David Pérez-Rey; Diana de la Iglesia; Víctor Maojo
Journal:  Biomed Res Int       Date:  2012-12-27       Impact factor: 3.411

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