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Literature DB >> 20817806

Selection and characterization of a multivalent Salmonella phage and its production in a nonpathogenic Escherichia coli strain.

S B Santos¹, E Fernandes, C M Carvalho, S Sillankorva, V N Krylov, E A Pleteneva, O V Shaburova, A Nicolau, E C Ferreira, J Azeredo.

Abstract

We report the selection and amplification of the broad-host-range Salmonella phage phi PVP-SE1 in an alternative nonpathogenic host. The lytic spectrum and the phage DNA restriction profile were not modified upon replication in Escherichia coli Bl21, suggesting the possibility of producing this phage in a nonpathogenic host, contributing to the safety and easier approval of a product based on this Salmonella biocontrol agent.

Entities: Species

Mesh：

Year: 2010 PMID： 20817806 PMCID： PMC2976242 DOI： 10.1128/AEM.00922-10

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

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