Literature DB >> 20816086

The long and short of fertility and longevity.

Yousin Suh1, Jan Vijg.   

Abstract

Does life span extension come with a reproductive trade-off? In a recent report published in Nature, Greer et al. (2010) show that in the nematode worm C. elegans, life span extension, as a consequence of deficiencies in histone methylation, requires an intact germline and ongoing fertility.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID: 20816086      PMCID: PMC2991055          DOI: 10.1016/j.cmet.2010.08.009

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  8 in total

1.  Regulation of life-span by germ-line stem cells in Caenorhabditis elegans.

Authors:  Nuno Arantes-Oliveira; Javier Apfeld; Andrew Dillin; Cynthia Kenyon
Journal:  Science       Date:  2002-01-18       Impact factor: 47.728

Review 2.  The genetics of ageing.

Authors:  Cynthia J Kenyon
Journal:  Nature       Date:  2010-03-25       Impact factor: 49.962

Review 3.  Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.

Authors:  Paul A C Cloos; Jesper Christensen; Karl Agger; Kristian Helin
Journal:  Genes Dev       Date:  2008-05-01       Impact factor: 11.361

4.  Fitness cost of extended lifespan in Caenorhabditis elegans.

Authors:  Nicole L Jenkins; Gawain McColl; Gordon J Lithgow
Journal:  Proc Biol Sci       Date:  2004-12-07       Impact factor: 5.349

Review 5.  Extending healthy life span--from yeast to humans.

Authors:  Luigi Fontana; Linda Partridge; Valter D Longo
Journal:  Science       Date:  2010-04-16       Impact factor: 47.728

6.  Signals from the reproductive system regulate the lifespan of C. elegans.

Authors:  H Hsin; C Kenyon
Journal:  Nature       Date:  1999-05-27       Impact factor: 49.962

7.  Human longevity at the cost of reproductive success.

Authors:  R G Westendorp; T B Kirkwood
Journal:  Nature       Date:  1998 Dec 24-31       Impact factor: 49.962

8.  Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.

Authors:  Eric L Greer; Travis J Maures; Anna G Hauswirth; Erin M Green; Dena S Leeman; Géraldine S Maro; Shuo Han; Max R Banko; Or Gozani; Anne Brunet
Journal:  Nature       Date:  2010-06-16       Impact factor: 49.962

  8 in total
  1 in total

1.  Aging, longevity and health.

Authors:  Lene Juel Rasmussen; Miriam Sander; Ulla M Wewer; Vilhelm A Bohr
Journal:  Mech Ageing Dev       Date:  2011-07-23       Impact factor: 5.432

  1 in total

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