Literature DB >> 20815688

The societal impact of pain in the European Union: health-related quality of life and healthcare resource utilization.

Paul Langley1, Gerhard Müller-Schwefe, Andrew Nicolaou, Hiltrud Liedgens, Joseph Pergolizzi, Giustino Varrassi.   

Abstract

OBJECTIVES: This paper reports on the results of a series of quantitative assessments of the association of severe and frequent pain with health-related quality of life and healthcare resource utilization in five European countries.
METHODS: The analysis contrasts the contribution of the increasing severity and frequency of pain reported against respondents reporting no pain in the previous month. The data are taken from the 2008 National Health and Wellness Survey. Single-equation generalized linear regression models are used to evaluate the association of pain with the physical and mental component scores of the SF-12 questionnaire as well as health utilities generated from the SF-6D. In addition, the role of pain is assessed in its association with healthcare provider visits, emergency room visits and hospitalizations.
RESULTS: The results indicate that the experience of pain, notably severe and frequent pain, is substantial and is significantly associated with the SF-12 physical component scores, health utilities and all aspects of healthcare resource utilization, which far outweighs the role of demographic and socioeconomic variables, health risk factors (in particular body mass index) and the presence of comorbidities. In the case of severe daily pain, the marginal contribution of the SF-12 physical component score is a deficit of -17.86 compared to those reporting no pain (population average score 46.49), while persons who are morbidly obese report a deficit of only -6.63 compared to those who are normal weight. The corresponding association with health utilities is equally dramatic with a severe daily pain deficit of -0.19 compared to those reporting no pain (average population utility 0.71).
CONCLUSIONS: For the five largest EU countries, the societal burden of pain is considerable. The experience of pain far outweighs the contribution of more traditional explanations of HRQoL deficits as well as being the primary factor associated with increased provider visits, emergency room visits and hospitalizations.

Entities:  

Mesh:

Year:  2010        PMID: 20815688     DOI: 10.3111/13696998.2010.516709

Source DB:  PubMed          Journal:  J Med Econ        ISSN: 1369-6998            Impact factor:   2.448


  31 in total

Review 1.  Intrathecal Analgesia for Chronic Refractory Pain: Current and Future Prospects.

Authors:  Catherine Smyth; Nadera Ahmadzai; Jason Wentzell; Ashley Pardoe; Andrew Tse; Tiffany Nguyen; Yvette Goddard; Shona Nair; Patricia A Poulin; Becky Skidmore; Mohammed T Ansari
Journal:  Drugs       Date:  2015-11       Impact factor: 9.546

2.  Pain in patients attending outpatient rehabilitation: results of a pilot study.

Authors:  Francesca Cecchi; Anita Paperini; Raffaello Molino Lova; Guido Pasquini; Roberta Boni; Chiara Castagnoli; Federica Vannetti; Luca Padua; Claudio Macchi
Journal:  Intern Emerg Med       Date:  2015-02-10       Impact factor: 3.397

3.  Role of nociceptor αCaMKII in transition from acute to chronic pain (hyperalgesic priming) in male and female rats.

Authors:  Luiz F Ferrari; Oliver Bogen; Jon D Levine
Journal:  J Neurosci       Date:  2013-07-03       Impact factor: 6.167

4.  Pain alleviation and patient-reported health outcomes following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain in routine medical practice.

Authors:  María T Saldaña; Concepción Pérez; Ana Navarro; Xavier Masramón; Javier Rejas
Journal:  Clin Drug Investig       Date:  2012-06-01       Impact factor: 2.859

5.  Healthcare utilization in chronic liver disease: the importance of pain and prescription opioid use.

Authors:  Shari S Rogal; Daniel Winger; Klaus Bielefeldt; Bruce L Rollman; Eva Szigethy
Journal:  Liver Int       Date:  2013-06-12       Impact factor: 5.828

6.  Chronic pain self-management support with pain science education and exercise (COMMENCE): study protocol for a randomized controlled trial.

Authors:  Jordan Miller; Joy C MacDermid; David M Walton; Julie Richardson
Journal:  Trials       Date:  2015-10-14       Impact factor: 2.279

Review 7.  Tramadol/Paracetamol fixed-dose combination for chronic pain management in family practice: a clinical review.

Authors:  Ignacio Morón Merchante; Joseph V Pergolizzi; Mart van de Laar; Hans-Ulrich Mellinghoff; Srinivas Nalamachu; Joanne O'Brien; Serge Perrot; Robert B Raffa
Journal:  ISRN Family Med       Date:  2013-04-11

Review 8.  A review of chronic pain impact on patients, their social environment and the health care system.

Authors:  María Dueñas; Begoña Ojeda; Alejandro Salazar; Juan Antonio Mico; Inmaculada Failde
Journal:  J Pain Res       Date:  2016-06-28       Impact factor: 3.133

Review 9.  Validity and responsiveness of EuroQol-5 dimension (EQ-5D) versus Short Form-6 dimension (SF-6D) questionnaire in chronic pain.

Authors:  Marko Obradovic; Arun Lal; Hiltrud Liedgens
Journal:  Health Qual Life Outcomes       Date:  2013-07-01       Impact factor: 3.186

10.  Pain Medicine in Crisis-A Possible Model toward a Solution: Empowering Community Medicine to Treat Chronic Pain.

Authors:  Amir Minerbi; Simon Vulfsons
Journal:  Rambam Maimonides Med J       Date:  2013-10-29
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