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Literature DB >> 20813433

Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.

Dorina Mantu¹, Mihaela Cătălina Luca, Costel Moldoveanu, Gheorghita Zbancioc, Ionel I Mangalagiu.

Abstract

A series of eighteen novel compounds with pyridazine moiety were synthesized and their in vitro antituberculosis activities have been evaluated. A fast, general, and facile method for preparation of pyridazine derivatives in moderate to excellent yields is presented. Three compounds were found to be moderate active against Mycobacterium tuberculosis. Correlation of structure-biological activity has been done.

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Year: 2010 PMID： 20813433 DOI： 10.1016/j.ejmech.2010.08.029

Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514

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Cited

8 in total

1. Ultrasound assisted synthesis of hybrid quinoline-imidazole derivatives: a green synthetic approach.

Authors: Dumitrela Diaconu; Dorina Amăriucăi-Mantu; Violeta Mangalagiu; Vasilichia Antoci; Gheorghita Zbancioc; Ionel I Mangalagiu
Journal: RSC Adv Date: 2021-11-29 Impact factor: 3.361

2. Hybrid Quinoline-Sulfonamide Complexes (M²⁺) Derivatives with Antimicrobial Activity.

Authors: Dumitrela Diaconu; Violeta Mangalagiu; Dorina Amariucai-Mantu; Vasilichia Antoci; Cristian Levente Giuroiu; Ionel I Mangalagiu
Journal: Molecules Date: 2020-06-26 Impact factor: 4.411

3. Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation.

Authors: Eman M Flefel; Waled A Tantawy; Walaa I El-Sofany; Mahmoud El-Shahat; Ahmed A El-Sayed; Dina N Abd-Elshafy
Journal: Molecules Date: 2017-01-17 Impact factor: 4.411

4. Antimycobacterial activity of nitrogen heterocycles derivatives: 7-(pyridine-4-yl)-indolizine derivatives. Part VII^8-12.

Authors: Anda-Mihaela Olaru; Violeta Vasilache; Ramona Danac; Ionel I Mangalagiu
Journal: J Enzyme Inhib Med Chem Date: 2017-12 Impact factor: 5.051

Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.

1. Ultrasound assisted synthesis of hybrid quinoline-imidazole derivatives: a green synthetic approach.

2. Hybrid Quinoline-Sulfonamide Complexes (M²⁺) Derivatives with Antimicrobial Activity.

3. Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation.

4. Antimycobacterial activity of nitrogen heterocycles derivatives: 7-(pyridine-4-yl)-indolizine derivatives. Part VII^8-12.

5. Microwave Assisted Reactions of Fluorescent Pyrrolodiazine Building Blocks.

Review 6. A Review on the Synthesis of Fluorescent Five- and Six-Membered Ring Azaheterocycles.

Review 7. Microwave Assisted Reactions of Azaheterocycles Formedicinal Chemistry Applications.

8. Huisgen [3 + 2] Dipolar Cycloadditions of Phthalazinium Ylides to Activated Symmetric and Non-Symmetric Alkynes.

Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.

1. Ultrasound assisted synthesis of hybrid quinoline-imidazole derivatives: a green synthetic approach.

2. Hybrid Quinoline-Sulfonamide Complexes (M2+) Derivatives with Antimicrobial Activity.

3. Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation.

4. Antimycobacterial activity of nitrogen heterocycles derivatives: 7-(pyridine-4-yl)-indolizine derivatives. Part VII8-12.

5. Microwave Assisted Reactions of Fluorescent Pyrrolodiazine Building Blocks.

Review 6. A Review on the Synthesis of Fluorescent Five- and Six-Membered Ring Azaheterocycles.

Review 7. Microwave Assisted Reactions of Azaheterocycles Formedicinal Chemistry Applications.

8. Huisgen [3 + 2] Dipolar Cycloadditions of Phthalazinium Ylides to Activated Symmetric and Non-Symmetric Alkynes.

2. Hybrid Quinoline-Sulfonamide Complexes (M²⁺) Derivatives with Antimicrobial Activity.

4. Antimycobacterial activity of nitrogen heterocycles derivatives: 7-(pyridine-4-yl)-indolizine derivatives. Part VII^8-12.