Literature DB >> 20811728

[Current developments in xenon research. Importance for anesthesia and intensive care medicine].

A Brücken1, M Coburn, S Rex, R Rossaint, M Fries.   

Abstract

The noble gas xenon exerts favorable anesthetic properties along with remarkable hemodynamic stability in healthy patients undergoing elective surgery. It represents the nearly ideal anesthetic and provides safe and well controllable anesthesia although the exact mechanism by which xenon produces anesthesia remains to be elucidated. In addition xenon offers organ protective properties for vital organs including the brain, heart and kidneys which seem to be synergistic when used in combination with therapeutic hypothermia. As the high cost of xenon will probably preclude its wider use as a routine anesthetic, data from extensive tests in large numbers of high risk patients is needed to confirm its possible superiority in this setting.

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Year:  2010        PMID: 20811728     DOI: 10.1007/s00101-010-1787-6

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  57 in total

1.  Prevention of neurotoxicity in hypoxic cortical neurons by the noble gas xenon.

Authors:  Christian Petzelt; Per Blom; Wolfgang Schmehl; Jana Müller; Wolfgang J Kox
Journal:  Life Sci       Date:  2003-03-14       Impact factor: 5.037

2.  Preliminary observations on the narcotic effect of xenon with a review of values for solubilities of gases in water and oils.

Authors:  J H Lawrence; W F Loomis; C A Tobias; F H Turpin
Journal:  J Physiol       Date:  1946-12-06       Impact factor: 5.182

3.  Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia.

Authors:  John Dingley; James Tooley; Helen Porter; Marianne Thoresen
Journal:  Stroke       Date:  2005-12-22       Impact factor: 7.914

4.  A practical rule for optimal flows for xenon anaesthesia in a semi-closed anaesthesia circuit.

Authors:  Anna B Roehl; Andreas Goetzenich; Rolf Rossaint; Norbert Zoremba; Marc Hein
Journal:  Eur J Anaesthesiol       Date:  2010-07       Impact factor: 4.330

5.  Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat.

Authors:  J L Martin; D Ma; M Hossain; J Xu; R D Sanders; N P Franks; M Maze
Journal:  Br J Anaesth       Date:  2007-01-08       Impact factor: 9.166

6.  Xenon does not modify mivacurium induced neuromuscular block.

Authors:  Oliver Kunitz; Jan-Hinrich Baumert; Klaus Hecker; Mark Coburn; Thorben Beeker; André Zühlsdorff; Jens Fassl; Rolf Rossaint
Journal:  Can J Anaesth       Date:  2005-11       Impact factor: 5.063

7.  Recovery from neuromuscular blockade after either bolus and prolonged infusions of cisatracurium or rocuronium using either isoflurane or propofol-based anesthetics.

Authors:  W S Jellish; M Brody; K Sawicki; S Slogoff
Journal:  Anesth Analg       Date:  2000-11       Impact factor: 5.108

8.  Xenon does not prolong neuromuscular block of rocuronium.

Authors:  Oliver Kunitz; Jan-Hinrich Baumert; Klaus Hecker; Thorben Beeker; Mark Coburn; André Zühlsdorff; Rolf Rossaint
Journal:  Anesth Analg       Date:  2004-11       Impact factor: 5.108

9.  The neuroprotective effects of xenon and helium in an in vitro model of traumatic brain injury.

Authors:  Mark Coburn; Mervyn Maze; Nicholas P Franks
Journal:  Crit Care Med       Date:  2008-02       Impact factor: 7.598

10.  Effect of xenon on cerebral autoregulation in pigs.

Authors:  M Schmidt; T Marx; C Papp-Jambor; U Schirmer; H Reinelt
Journal:  Anaesthesia       Date:  2002-10       Impact factor: 6.955

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  4 in total

1.  [Xenon revisited].

Authors:  P Conzen
Journal:  Anaesthesist       Date:  2010-10       Impact factor: 1.041

2.  Cerebral oxygen saturation is improved by xenon anaesthesia during carotid clamping.

Authors:  G Godet; A Couaud; A Lucas; A Cardon; H Beloeil; C Ecoffey
Journal:  HSR Proc Intensive Care Cardiovasc Anesth       Date:  2013

3.  Better haemodynamic stability under xenon anaesthesia than under isoflurane anaesthesia during partial nephrectomy - a secondary analysis of a randomised controlled trial.

Authors:  Patrick Schäfer; Astrid Fahlenkamp; Rolf Rossaint; Mark Coburn; Ana Kowark
Journal:  BMC Anesthesiol       Date:  2019-07-09       Impact factor: 2.217

4.  Exploring the Effects on Lipid Bilayer Induced by Noble Gases via Molecular Dynamics Simulations.

Authors:  Junlang Chen; Liang Chen; Yu Wang; Xiaogang Wang; Songwei Zeng
Journal:  Sci Rep       Date:  2015-11-25       Impact factor: 4.379

  4 in total

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