Literature DB >> 2080983

Transdermal drug delivery: efficacy and potential applications of the penetration enhancer Azone.

J W Wiechers1, R A de Zeeuw.   

Abstract

In this review, the properties, pharmaceutical profile, and metabolism of Azone are described, and the mechanism of its action in facilitating transdermal drug delivery is discussed. It is concluded that the compound is safe for human use, and of value in enhancing the cutaneous absorption of many types of drugs.

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Year:  1990        PMID： 2080983

Source DB:  PubMed          Journal:  Drug Des Deliv        ISSN： 0884-2884


  7 in total

Review 1.  Getting Drugs Across Biological Barriers.

Authors:  Rong Yang; Tuo Wei; Hannah Goldberg; Weiping Wang; Kathleen Cullion; Daniel S Kohane
Journal:  Adv Mater       Date:  2017-07-28       Impact factor: 30.849

2.  Synthesis and enhancing effect of transkarbam 12 on the transdermal delivery of theophylline, clotrimazole, flobufen, and griseofulvin.

Authors:  Alexandr Hrabálek; Pavel Dolezal; Katerina Vávrová; Jarmila Zbytovská; Tomás Holas; Jana Klimentová; Jakub Novotný
Journal:  Pharm Res       Date:  2006-05-02       Impact factor: 4.200

3.  Effects of chemical enhancers on human epidermal membrane: Structure-enhancement relationship based on maximum enhancement (E(max)).

Authors:  Sarah A Ibrahim; S Kevin Li
Journal:  J Pharm Sci       Date:  2009-03       Impact factor: 3.534

4.  Hydration effects on skin microstructure as probed by high-resolution cryo-scanning electron microscopy and mechanistic implications to enhanced transcutaneous delivery of biomacromolecules.

Authors:  Grace Tan; Peng Xu; Louise B Lawson; Jibao He; Lucia C Freytag; John D Clements; Vijay T John
Journal:  J Pharm Sci       Date:  2010-02       Impact factor: 3.534

Review 5.  Current Status of Amino Acid-Based Permeation Enhancers in Transdermal Drug Delivery.

Authors:  Rui Pereira; Sandra G Silva; Marina Pinheiro; Salette Reis; M Luísa do Vale
Journal:  Membranes (Basel)       Date:  2021-05-07

6.  Synergistic efficacy of salicylic acid with a penetration enhancer on human skin monitored by OCT and diffuse reflectance spectroscopy.

Authors:  Qingliang Zhao; Cuixia Dai; Shanhui Fan; Jing Lv; Liming Nie
Journal:  Sci Rep       Date:  2016-10-10       Impact factor: 4.379

7.  Structure Enhancement Relationship of Chemical Penetration Enhancers in Drug Transport across the Stratum Corneum.

Authors:  Doungdaw Chantasart; S Kevin Li
Journal:  Pharmaceutics       Date:  2012-01-17       Impact factor: 6.321
  7 in total

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