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Literature DB >> 20809390

Heart rate reduction in cardiovascular disease and therapy.

Jan-Christian Reil¹, Florian Custodis, Karl Swedberg, Michel Komajda, Jeffrey S Borer, Ian Ford, Luigi Tavazzi, Ulrich Laufs, Michael Böhm.

Abstract

Heart rate influences myocardial oxygen demand, coronary blood flow, and myocardial function. Clinical and experimental studies support an association between elevated resting heart rate and a broad range of maladaptive effects on the function and structure of the cardiovascular system. Heart rate has been shown to be an important predictor of mortality in cardiovascular disorders such as coronary artery disease, myocardial infarction, and chronic heart failure. This review summarizes the specific influence of heart rate on vascular morphology and function as well as on myocardial lesions leading from early impact on vascular homeostasis to myocardial hemodynamics in chronic heart failure. Heart rate can be easily determined during physical examination of the patient and therefore allows a simple hint on prognosis and efficiency of therapy.

Entities: Chemical Disease Species

Mesh：

Year: 2010 PMID： 20809390 DOI： 10.1007/s00392-010-0207-x

Source DB: PubMed Journal: Clin Res Cardiol ISSN： 1861-0684 Impact factor: 5.460

51 in total

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Journal: J Am Coll Cardiol Date: 2005-01-18 Impact factor: 24.094

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39 in total

1. Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study.

Authors: Robert S Hoke; Ursula Müller-Werdan; Christine Lautenschläger; Karl Werdan; Henning Ebelt
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Review 2. Renal sympathetic denervation: applications in hypertension and beyond.

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Journal: Clin Res Cardiol Date: 2012-10-12 Impact factor: 5.460

Review 4. Novel and nonpharmacologic approaches to cardio-protection in hypertension.

Authors: Luca Donazzan; Felix Mahfoud; Dominik Linz; Sebastian Ewen; Christian Ukena; Michael Böhm
Journal: Curr Hypertens Rep Date: 2014-05 Impact factor: 5.369

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Authors: Eva M Lonn; Sherryn Rambihar; Peggy Gao; Florian F Custodis; Karen Sliwa; Koon K Teo; Salim Yusuf; Michael Böhm
Journal: Clin Res Cardiol Date: 2013-12-20 Impact factor: 5.460

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Journal: Heart Fail Rev Date: 2018-07 Impact factor: 4.214

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Journal: Clin Res Cardiol Date: 2012-03-07 Impact factor: 5.460