Literature DB >> 20807958

Interpretation of interactions: guide for the perplexed.

Kenneth S Kendler, Charles O Gardner.   

Abstract

In this issue, Zammit et al explore how five dichotomised risk factors work together to predict risk for non-affective psychosis in a large Swedish cohort. In this editorial, we review these findings, and comment on both the nature of additive v. multiplicative models and the meaning of statistical interactions.

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Year:  2010        PMID： 20807958     DOI： 10.1192/bjp.bp.110.081331

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN： 0007-1250            Impact factor:   9.319


  48 in total

1.  IQ and schizophrenia in a Swedish national sample: their causal relationship and the interaction of IQ with genetic risk.

Authors:  Kenneth S Kendler; Henrik Ohlsson; Jan Sundquist; Kristina Sundquist
Journal:  Am J Psychiatry       Date:  2014-11-07       Impact factor: 18.112

2.  Personality diathesis explains the interrelationships between personality disorder and other mental conditions.

Authors:  Peter Tyrer
Journal:  World Psychiatry       Date:  2011-06       Impact factor: 49.548

3.  Genetic variants in 5-HTTLPR, BDNF, HTR1A, COMT, and FKBP5 and risk for treated depression after cancer diagnosis.

Authors:  Nis P Suppli; Jens D Bukh; Terrie E Moffitt; Avshalom Caspi; Christoffer Johansen; Anne Tjønneland; Lars V Kessing; Susanne O Dalton
Journal:  Depress Anxiety       Date:  2017-06-07       Impact factor: 6.505

4.  An extended Swedish national adoption study of alcohol use disorder.

Authors:  Kenneth S Kendler; Jianguang Ji; Alexis C Edwards; Henrik Ohlsson; Jan Sundquist; Kristina Sundquist
Journal:  JAMA Psychiatry       Date:  2015-03       Impact factor: 21.596

5.  Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study.

Authors:  Sinan Guloksuz; Lotta-Katrin Pries; Philippe Delespaul; Gunter Kenis; Jurjen J Luykx; Bochao D Lin; Alexander L Richards; Berna Akdede; Tolga Binbay; Vesile Altınyazar; Berna Yalınçetin; Güvem Gümüş-Akay; Burçin Cihan; Haldun Soygür; Halis Ulaş; EylemŞahin Cankurtaran; Semra Ulusoy Kaymak; Marina M Mihaljevic; Sanja Andric Petrovic; Tijana Mirjanic; Miguel Bernardo; Bibiana Cabrera; Julio Bobes; Pilar A Saiz; María Paz García-Portilla; Julio Sanjuan; Eduardo J Aguilar; José Luis Santos; Estela Jiménez-López; Manuel Arrojo; Angel Carracedo; Gonzalo López; Javier González-Peñas; Mara Parellada; Nadja P Maric; Cem Atbaşog Lu; Alp Ucok; Köksal Alptekin; Meram Can Saka; Celso Arango; Michael O'Donovan; Bart P F Rutten; Jim van Os
Journal:  World Psychiatry       Date:  2019-06       Impact factor: 49.548

6.  Maternal prenatal smoking and offspring emotional problems: no moderating effect of maternal or child 5-HTTLPR genotype.

Authors:  Lot M Geels; Maria M Groen-Blokhuis; Catharina E M van Beijsterveldt; Jacqueline M Vink; Christel M Middeldorp; Meike Bartels; Kelly A Nelson; Patricia E Huizenga; Gareth E Davies; Dorret I Boomsma
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2012-10-22       Impact factor: 3.568

Review 7.  The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research.

Authors:  Conrad Iyegbe; Desmond Campbell; Amy Butler; Olesya Ajnakina; Pak Sham
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2014-01-17       Impact factor: 4.328

Review 8.  Genetic epidemiology and insights into interactive genetic and environmental effects in autism spectrum disorders.

Authors:  Young Shin Kim; Bennett L Leventhal
Journal:  Biol Psychiatry       Date:  2014-11-05       Impact factor: 13.382

9.  Are major behavioral and sociodemographic risk factors for mortality additive or multiplicative in their effects?

Authors:  Neil Mehta; Samuel Preston
Journal:  Soc Sci Med       Date:  2016-02-16       Impact factor: 4.634

10.  Peer deviance, parental divorce, and genetic risk in the prediction of drug abuse in a nationwide Swedish sample: evidence of environment-environment and gene-environment interaction.

Authors:  Kenneth S Kendler; Henrik Ohlsson; Kristina Sundquist; Jan Sundquist
Journal:  JAMA Psychiatry       Date:  2014-04       Impact factor: 21.596
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