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Literature DB >> 20803155

Rotenoids from Lablab purpureus L. and their bioefficacy against human disease vectors.

Abstract

Various plant parts of Lablab purpureu s L. were collected and analyzed separately for their rotenoid content. Among the plant parts, the maximum content was in the roots and minimum in the seeds. The identity of different rotenoids was confirmed by melting point, mixed melting point, UV, and infrared spectral studies and gas-liquid chromatography. Six rotenoids (deguelin, dehydrodeguelin, rotenol, rotenone, tephrosin, and sumatrol) were isolated, identified, and quantified both in vivo and in vitro. Toxicological studies of extracts showed bioefficacy against causal agents of malaria, dracunculiasis, and amoebiasis.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2010 PMID： 20803155 DOI： 10.1007/s00436-010-2023-7

Source DB: PubMed Journal: Parasitol Res ISSN： 0932-0113 Impact factor: 2.289

12 in total

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Authors: A Abdul Rahuman; Geetha Gopalakrishnan; P Venkatesan; Kannappan Geetha
Journal: Parasitol Res Date: 2007-12-29 Impact factor: 2.289

Rotenoids from Lablab purpureus L. and their bioefficacy against human disease vectors.

Review 1. Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world.

2. Dracunculiasis eradication--global surveillance summary, 2008.

3. WHO/PAHO/UNESCO report. A consultation with experts on amoebiasis. Mexico City, Mexico 28-29 January, 1997.

4. Chonemorphine and rapanone--antiparasitic agents from plant sources.

5. Rotenoids from indigofera tinctoria and their bio-efficacy against cyclops, the carrier of dracunculiasis.

6. In vitro amoebicidal testing of natural products; Part I. Methodology.

7. Phytoextract-induced developmental deformities in malaria vector.

8. Larvicidal activity of some Euphorbiaceae plant extracts against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae).

9. Larvicidal activity of leguminous seeds and grains against Aedes aegypti and Culex pipiens pallens.

10. Chemical constituents of Pyrrosia petiolosa.

1. Larvicidal activity and in vitro regulation of rotenoids from Cassia tora L.

2. Mosquito larvicidal activity of citrus limonoids against Aedes albopictus.