Literature DB >> 20801234

PorA VR3 Typing Database: a web-based resource for the determination of PorA VR3 alleles of Neisseria meningitidis.

Ivano de Filippis1, Vivek Gopalan, Yentram Huyen.   

Abstract

The variable regions (VR) of the surface-exposed PorA protein of Meningococci are used for subtyping and are considered the most abundant epitopes of outer membrane vesicle-based vaccine preparations. We have developed both a database that maintains all the known VR3 alleles and a web-based application for the rapid identification and submission of new VR3 variants based on sequence comparison.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20801234     DOI: 10.1016/j.meegid.2010.08.011

Source DB:  PubMed          Journal:  Infect Genet Evol        ISSN: 1567-1348            Impact factor:   3.342


  5 in total

1.  Genetic characteristics of Neisseria meningitidis serogroup B strains carried by adolescents living in Milan, Italy: implications for vaccine efficacy.

Authors:  Susanna Esposito; Alberto Zampiero; Leonardo Terranova; Valentina Montinaro; Alessia Scala; Valentina Ansuini; Nicola Principi
Journal:  Hum Vaccin Immunother       Date:  2013-07-23       Impact factor: 3.452

2.  Invasive serogroup B Neisseria meningitidis in Quebec, Canada, 2003 to 2010: persistence of the ST-269 clone since it first emerged in 2003.

Authors:  Jianwei Zhou; Brigitte Lefebvre; Saul Deng; Rodica Gilca; Genevieve Deceuninck; Dennis K S Law; Philippe De Wals; Raymond S W Tsang
Journal:  J Clin Microbiol       Date:  2012-02-15       Impact factor: 5.948

3.  Characterization of invasive Neisseria meningitidis strains from Québec, Canada, during a period of increased serogroup B disease, 2009-2013: phenotyping and genotyping with special emphasis on the non-carbohydrate protein vaccine targets.

Authors:  Dennis K S Law; Brigitte Lefebvre; Rodica Gilca; Saul Deng; Jianwei Zhou; Philippe De Wals; Raymond S W Tsang
Journal:  BMC Microbiol       Date:  2015-07-25       Impact factor: 3.605

4.  Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2.

Authors:  Noha M Abouseada; Mahde Saleh A Assafi; Jafar Mahdavi; Neil J Oldfield; Lee M Wheldon; Karl G Wooldridge; Dlawer A A Ala'Aldeen
Journal:  PLoS One       Date:  2012-09-25       Impact factor: 3.240

5.  Characterization of invasive Neisseria meningitidis from Atlantic Canada, 2009 to 2013: With special reference to the nonpolysaccharide vaccine targets (PorA, factor H binding protein, Neisseria heparin-binding antigen and Neisseria adhesin A).

Authors:  Raymond Sw Tsang; Dennis Ks Law; Rita R Gad; Tim Mailman; Gregory German; Robert Needle
Journal:  Can J Infect Dis Med Microbiol       Date:  2015 Nov-Dec       Impact factor: 2.471

  5 in total

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