A questionnaire on pelvic floor dysfunction postpartum.

INTRODUCTION AND HYPOTHESIS: the incidence of obstetric anal sphincter injuries is used in Sweden as a measurement of quality of care and this might influence the reporting. However, the correlation between reported diagnosis of pelvic floor injury at delivery and pelvic floor symptoms a year later is unknown. A questionnaire could identify such symptoms and provide beneficial feedback to obstetrical practices.
METHODS: we made a cross-sectional study by sending out a questionnaire about pelvic floor dysfunction to 599 women depending on reported injury at delivery. The answers provided by the groups were then compared.
RESULTS: the questionnaire identified women with pelvic floor dysfunction. Anal incontinence was most common among women with obstetric anal sphincter injuries but also occurred among women delivered vaginally without known tears.
CONCLUSION: we suggest that a questionnaire is used 12-18 months after delivery to establish the short-time outcome in terms of pelvic floor dysfunction.

Introduction

Female pelvic floor dysfunction with symptoms such as urinary and anal incontinence as well as prolapse symptoms causes major discomfort and embarrassment [1-4]. Vaginal delivery in itself and large tears in the pelvic floor and perineum in particular are important contributing factors. Obstetric anal sphincter injuries (OASIS) have received increasing attention during the last two decades [5-7]. The reported incidence of clinically detected OASIS varies from 0.36% of vaginal deliveries in Finland [8] to 6% [9, 10] in other western countries. Delivering your first baby is the greatest risk factor for OASIS [9, 11, 12] and among primiparous women the incidence has been reported to be as high as 24% [13, 14]. With the addition of endoanal ultrasonography as a diagnostic tool when examining women, the incidence of diagnosed OASIS increases to about 40% [6, 14, 15].

In Sweden the incidence of OASIS has been reported annually to the National Board of Swedish Health and Welfare and also to the Stockholm County Council since 1990 as a measurement of quality of obstetric care. The value of this reported figure is open to debate, since the incidence increases during study periods indicating that greater knowledge about the condition may enhance the ability to identify and willingness to report every OASIS [9, 13, 14, 16]. A low figure may consequently reflect good obstetric care but can also possibly be an indication of overlooked cases of OASIS, and the figure might thus be ambiguous in terms of a measurement of quality. Considering the fact that diagnosing otherwise overlooked OASIS reduces the risk of anal incontinence after childbirth [15], we could presume that second best, after prevention of OASIS, is at least detection followed by suturing. We therefore made the assumption that purely striving for a low incidence of OASIS is questionable, and that a tool to measure quality of obstetric care in terms of pelvic floor dysfunction symptoms would be of value. We offered, and were commissioned by, the Stockholm County Council to construct a questionnaire and to evaluate if it could be used as a tool for detecting symptoms of OASIS and its complications, giving a more accurate assessment of quality of delivery care than the incidence alone.

Material and methods

OASIS is divided into 4 degrees (16 WHO1992). The first degree involves only the vaginal mucous membrane and the perineal skin, and the second-degree tear involves the fascia and muscle of the perineal body but not the anal sphincters. The third degree tear involves the anal sphincters and is further divided into (1) a partial tear of the anal sphincters and (2) a complete tear of the external and internal anal sphincters. The fourth-degree tear involves the anal or rectal mucosa.

The outline of the study design is shown in Fig. 1. The study was based on all primiparas delivered from April 1 2006 to March 31 2007 in the Stockholm County in which all six delivery units share the same computerized medical record system and which is connected to a statistical program, Business Object (BO). Through BO we could trace the desired target groups. The questionnaire was sent out during two periods: in October 2007, reaching women delivered from April 1st 2006 until September 30th 2006, and in April 2008 reaching women who gave birth from October 1st 2006 until March 30th 2007. We wanted the questionnaire to reach the women 12–18 months after their first delivery since we assumed that, at this time, most women have stopped breastfeeding, they menstruate again, lacerations are healed and further improvement of symptoms from the pelvic floor cannot be expected. In addition, most women have not yet delivered a second time.

Fig. 1

Outline of study design and participants accrual

The incidence of OASIS in vaginally delivered primiparas in Stockholm during 2006 was reported to be 7.6% in the National Medical Birth Register. From this the estimated number of women sustaining a complete OASIS during the study period was calculated to be approximately 140. All women who were diagnosed as having sustained a complete obstetric anal sphincter injury (degree IIIB and degree IV) were invited and comprised group 1, (n = 106).

Women randomly selected among those who sustained a partial OASIS (degree IIIA) constituted group 2 (n = 137). As control groups we used randomly selected women delivered by either elective cesarean section due to breech presentation (group 3 (n = 176)) or by a normal vaginal delivery without a diagnosed tear larger than grade 2 (group 4 (n = 184).Women delivered before gestational week 37 or with an intrauterine fetal death were excluded. The oversampling of women delivered vaginally with no reported OASIS and by elective cesarean section was done to increase the efficiency of the study since we suspected they might report fewer symptoms. All women were sent the questionnaire by mail and the women who failed to respond were sent two reminders.

The questionnaire consisted of three parts, the first including four questions which had previously been used to identify women with urinary leakage or prolapse [17, 18]. The questions about urinary leakage were: “Do you occasionally experience urinary leakage?” (U1); and “Did you experience urinary leakage before pregnancy?” (U2). “Do you occasionally experience an emergent need to urinate and then have difficulties reaching the toilet in time?” (U3) An additional question was; “Do you leak urine when coughing, sneezing, lifting or during physical activities?” (U4)

For urinary incontinence we used the answer alternatives “never”, “some time every month”, “some time every week”, and “daily”. Incontinence once a week or more often was used as the definition of incontinence, in line with the suggestion by Fornell et al. [19] that this definition could be used in populations where objective signs are not available on record. An affirmative answer to question U4 served to define stress urinary incontinence (SUI) and an affirmative answer to question U3 served to define urge urinary incontinence (UUI).

For prolapse symptoms we used the question “Do you have a sensation of tissue protrusion (vaginal bulge) from the vagina” (U5) with the answer alternatives “no”, ”some time every month”, “some time every week”, “daily”. The answer “some time every week” or “daily” served to define symptoms and”no” or”once a month” defined no symptoms.

The second part of the questionnaire dealt with anal incontinence using the modified Wexner score [20] which includes questions about involuntary leakage of gas, liquid and solid stools, the need to wear pads and if lifestyle alterations are being made due to incontinence. These questions have not been validated in Swedish but are frequently used in similar studies in other languages [10, 15, 21].

For anal incontinence we used four questions: “Do you occasionally experience solid stools leakage?” (A1) “Do you occasionally experience liquid stools leakage?”(A2) “Do you occasionally involuntarily leak gas” (A3) and “Do you use pads due to bowel leakage?” (A4) For lifestyle alterations we asked “Is there anything that you must avoid due to anxiety about gas –and/or anal leakage, for example walks, physical activity, swimming, courses or professional work?” (A5) The answer alternatives were: “no”, “some time every month”, “some time every week”, and “daily”. For anal incontinence the answers “some time every month” or “some time every week” or “daily” served to define symptoms, since we postulated that fertile women very seldom report anal incontinence and also that infrequent fecal leakage is bothersome [5].

The third part concerned background data about height, weight, self-evaluated health, native language and level of education. The BMI variable was divided in four categories; <19, 19–25, >25–30, and >30.

To test the comprehensibility of the questionnaire we randomly selected two to three women in each of the four study groups, ten women in all. During a personal meeting they filled in the questionnaire together with one of the members of the study group specialized in validating forms. In this pilot study the questions proved to be understandable and the alternatives easily distinguishable.

Statistics: The difference in proportion of symptomatic women between the two populations in groups 1 and 2 was set at 0.20, as this was the smallest effect that would be clinically important to detect. Assuming the above-mentioned difference in proportions, 93 patients were needed in each group, given that the significance level was set at 5%, and the power at 80%.”The statistical method used was Chi-square test or Fisher's exact test when the expected value in the cells was more than 1 (which was the case primarily in the questions about incontinence). One-way analysis of variance was used to evaluate any contingent difference in (mean) BMI between the four groups. Statistical computing was done using SPSS version 17.

The study was approved by The Ethics Committee at Karolinska Institutet (2007/1228-31/4 October 31st 2007)

Results

The questionnaire was completed by the same percentage of women in all the groups, in total 366 women, giving a response rate of 61.1% (Fig. 1). Mean age and diagnosis among responders and non-responders is presented in Table 1 which shows that there were no significant differences between the groups in this respect.

Table 1

Mean age (range) and diagnosis for responders and non-responders

	Age of responders (N (366))	Age of non-responders (N (229))
Group 1, complete OASIS	32.2 (24–41)	30 (18–40)
Group 2, partial OASIS	30.2 (20–40)	29 (20–41)
Group 3, elective c-section	30.5 (19–46)	32.2 (19–44)
Group 4, vaginal delivery tear <2nd degree	31.3 (20–41)	30.6 (18–42)

Obstetric anal sphincter ruptures (OASIS)

The background data are presented in Table 2. Out of the 366 women 16.3% (54) were pregnant again when answering the questionnaire; 63.7% (232) of the women were university graduates.BMI was categorized into four intervals but no significant differences between the groups were seen in any of the background parameters.

Table 2

Cross-tabulation demographic percentage of data (n)

	Complete OASIS group (1% (n))	Partial OASIS group (2% (n))	Elective C-s group (3% (n))	Vaginal delivery tear <2 degree group (4% (n))	P value
Are you pregnant now?					0.668
Yes	19.7 (12)	18.2 (16)	13.7 (14)	14.3 (16)
No	80.3 (49)	81.8 (72)	86.3 (88)	85.7 (96)
BMI					0.053
<19	6.5 (4)	8.0 (7)	11.9 (12)	6.3 (7)
19–25	72.6 (45)	65.5 (57)	63.4(64)	70.3 (78)
>25–30	17.7 (11)	21.8 (19)	12.9 (13)	21.6 (24)
>30	3.2 (2)	4.6 (4)	11.9 (12)	1.8 (2)
Self-assessed health					0.722
Excellent	11.3 (7)	19.3 (17)	18.0 (18)	24.1 (27)
Very good	54.8 (34)	46.6(41)	48.0 (48)	49.1 (55)
Good	27.4 (17)	28.4 (25)	26.0 (26)	22.3 (25)
Fair	6.5 (4)	3.4 (3)	7.0 (7)	3.6 (4)
Poor	0.0 (0)	2.3 (2)	1.0 (1)	0.9 (1)
Is Swedish your native language?					0.0537
Yes	87.1 (54)	78.4 (69)	84.3 (86)	82.3 (93)
No	12.9(8)	21.6 (19)	15.7 (16)	17.7 (20)
Highest completed education					0.163
Elementary school	3.2 (2)	6.8 (6)	4.0 (4)	1.8 (2)
High school	21.0 (13)	31.8 (28)	32.7 (33)	38.9 (44)
University	75.8 (47)	6.4 (54)	63.4 (64)	59.3 (67)

There were no differences between the groups concerning background data. Body mass index (BMI), obstetric anal sphincter ruptures (OASIS)

Urinary incontinence

Very few women reported urinary leakage before pregnancy and there were no differences between the groups (Table 3).

Table 3

Urinary incontinence reported in the four different groups

	Complete OASIS group (1% (n))	Partial OASIS group (2% (n))	Elective c-s group (3% (n))	Vaginal delivery, tear <2 degree group (4% (n))	P value
U1 occasionally leak urine					0.093
No/every month	81.7 (49)	81.8 (72)	93.0 (93)	86.6 (97)
every week/daily	18.3 (11)	18.2 (16)	7 (7)	13.4 (15)
U2 before pregnancy					0.124
no/every month	95.2 (59)	100	97.0 (98)	99.1 (112)
every week/daily	4.8 (3)	0	3.0 (3)	0.9 (1)
U3 Urge incontinence					0.426
No/every month	91.8 (56)	89.8 (79)	94.1 (96)	87.7 (100)
Every week/daily	8.2 (5)	10.2 (9)	5.9 (6)	12.3 (14)
U4 Stress incontinence					0.019
No/every month	80.6 (50)	87.5 (77)	96.0 (97)	86.0 (98)
Every week/daily	19.4 (12)	12.5 (11)	4.0 (4)	14.0 (16)
U5 vaginal bulge					0.010
No/every month	90.2 (55)	97.7 (86)	100.0	95.5 (107)
Every week/daily	9.8 (6)	2.3 (2)	0 (102)	4.5 (5)

There were no differences between the groups before pregnancy. Stress urinary incontinence and prolapse symptoms were seldom noted among women delivered by a caesarean section, but were among women with any vaginal tear. Note that women with no reported obstetric anal sphincter rupture (OASIS) also complained of prolapse symptoms which might indicate missed OASIS or severe vaginal tears

Occasional leakage of urine was reported to be equally common in each group 1 year postpartum. Urge urinary incontinence (UUI) was not significantly different between the groups either and was reported by 8.2% (5) in group 1 and 10.2% (9) in group 2, by 5.9% (6) in group 3 and by 12.3% (14) in group 4 (n.s.).

The significantly lowest incidence of stress urinary incontinence (SUI) was found among women in group 3 and was reported weekly/daily by 19.4% (12) in group 1, 12.5% (11)in group 2, 4.0% (4) in group 3 and 14.0% (16) in group 4 (P = 0.019) (Table 3).

Prolapse symptoms

The sense of vaginal bulge was significantly higher in group 1 which comprised those who had a complete OASIS compared to group 2. No one in group 3 reported this complaint. Notably five women in group 4 reported prolapse symptoms 1 year postpartum (Table 3).

Anal incontinence

In this survey none of the women who sustained a complete OASIS suffered from frank solid stool leakage 12–18 months after their first delivery while 4.5% (4) in group 2, 1.0% (1) in group 3, and notably 2.6% (3) in group 4 reported solid stool leakage (p = 0,218) (Table 4).

Table 4

Anal incontinence in the four different groups

	Complete OASIS	Partial OASIS	Elective caesarean section	Vaginal delivery tear <2 degree	P value
	Group 1	Group 2	Group 3	Group 4
A1 solid stools					0.218
No	100 (61)	95.5 (84)	99.0 (101)	97.4 (111)
Every month/every week/daily	0	4.5 (4)	1.0 (1)	2.6 (3)
A2 liquid stools					0.004
No	82.3 (51)	83.0 (73)	94.1 (96)	94.7 (108)
Every month/every week/daily	17.7 (11)	17.0 (15)	5.9 (6)	5.3 (6)
A3 gas					<0.000
No	24.2 (15)	46.6 (41)	72.5 (74)	69.0 (78)
Every month/every week/daily	75.8 (47)	53.4 (47)	27.5 (28)	31.0 (35)
A4 pads					0.011
No	93.5 (58)	98.9 (87)	99.0 (101)	100.0 (113)
Every month/every week/daily	6.5 (4)	1.1 (1)	1.0 (1)	0
A5 lifestyle alteration					0.075
No	88.7 (55)	95.5 (84)	96.1 (98)	97.4 (111)
Every month/every week/daily	11.3 (7)	4.5 (4)	3.9 (4)	2.6 (3)

Leakage of liquid stools was more often observed among women with obstetric anal sphincter ruptures (OASIS). Also leakage of gas was more common in these two groups, while women in the group having had a complete OASIS more often used sanitary pads

The symptom of liquid stools leakage was more frequent and was reported mainly among women with a reported obstetric tear; by 17.7% (11) women in group 1, 17.0% (15) in group 2 and six women each in groups 3 and 4; 5.9% and 5.3%, respectively (P = 0.004).The symptom of flatus incontinence occurred in 75.8% (47) of women in group 1, 53.4% (47) in group 2, 27.5% (28) in group 3 and 31% (35) in group 4 (P = 0,000) (Table 4).

The need to wear pads was significantly more often reported by women with a severe OASIS, group 1 (6.5% (4), P = 0,011) (Table 4). When testing frequency of symptoms in terms of no/every month/every week/daily and comparing the groups the results did not change, however the groups were very small, see Table 5.

Table 5

Descriptive statistics

	Complete OASIS		Partial OASIS	Elective caesarean section	Vaginal delivery, tear <2 degree			Number		P value
	n = 61	n = 62	n = 88	n = 102	n = 111	n = 113	n = 114	Total = 365	Total = 366
A1 solid stools										0.328
No	61		84	101	111			357
Every month	0		3	0	2			5
Every week	0		0	1	1			2
Daily	0		1	0	0			1
A2 liquid stools										0.002
No		51	73	96			108		328
Every month		8	15	5			5		33
Every week		2	0	1			0		2
Daily		1	0	0			1		2
A3 gas										<0.001
No		15	41	74				208
Every month		15	22	21				83
Every week		25	19	6				55
Daily		7	6	1				19
A4 pads										0.016
No		58	87	101		78			359
Every month		1	1	0		25			2
Every week		1	0	0		5			1
Daily		2	0	1		5			3
A5 lifestyle alteration										0.055
No		55	84	98		113	111		348
Every month		6	1	3		0	2		12
Every week		0	1	1		0	0		2
Daily		1	2	0		0	1		4

Anal incontinence in the four groups. Since there are few women in each group reporting symptoms, interpretation of data is difficult

Discussion

We found it a challenge to evaluate the women’s experiences of pelvic floor symptoms in relation to the reported perineal tear after delivery. Sampling four groups of women with reported different severity of the perineal tear, we assumed that the answers would represent the obstetric trauma. Our hypothesis was that a high incidence of symptoms would be found in the two groups with a known OASIS, a hypothesis that held true. As we expected, women in group 3 reported almost no symptoms. Interestingly, women in group 4 reported symptoms to some extent which might be an indication of missed injuries. Since the study is not dealing with causalities there is a risk that it might reveal women with comorbidities.

In Sweden the incidence of obstetric anal sphincter injuries, OASIS, in each delivery department is reported annually to the Swedish National Board of Health and Welfare and a low incidence is considered to be an indicator of good quality of obstetric care. Until recently, this report has merely been a concern for each department, but during the latest years the figures have been published in the newspapers, and since 2009 there is open competition between the six delivery departments, where a low OASIS figure could be presented as a benefit when offering obstetric care. Worldwide, there are reports of increasing incidence of OASIS. Studies have been presented revealing increasing incidence in the event of women going through thorough reexamination by an experienced clinician immediately after delivery, [13, 14]. It is thus possible that an increasing incidence may merely reveal a high level of knowledge about the condition.

It is most important to prevent any birth trauma if possible but the worse trauma is that which has not been detected and treated. An evaluation of women’s experience of short-and/or long-term pelvic floor symptoms after delivery would be more valuable as an indicator of quality of obstetric care than the reported incidence alone.

The strength of the present study is that the population consisted of a sample of all primiparas who gave birth in Stockholm during the study period and the fact that all women who sustained a complete OASIS were invited to participate in the survey. Moreover, the division of OASIS into two subgroups might allow us to reason around contingent differences between symptoms following these two injuries. This distinction is rare in previous literature. We also involved two well-defined control groups. Another strength is that the mean age of the groups is approximately the same. The study does not however deal in any way with causalities such as maternal age, fetal size, or comorbidities but only with the possibility of identifying pelvic floor symptoms probably caused by delivery.

Two thirds of the women were university graduates, a figure that reflects the educational level in large cities in Sweden and indicates that we reached a representative sample of women giving birth in Stockholm. The period 12–18 months after delivery for the short-time follow-up was selected arbitrarily due to the fact that most women had been menstruating for some periods at 1 year postpartum but had still not delivered a second time. The result of the questionnaire will if used, provide the delivery department with fairly swift feedback. On the other hand, a weakness of the study was the low response rate which raised the suspicion that non-responders had few symptoms of pelvic floor dysfunction.

The groups did not differ regarding urinary incontinence before delivery. It is well-established that the prevalence of UI varies greatly depending on study group, definitions and methods used [22]. The prevalence of urinary incontinence during pregnancy is reported to be as high as 44% and between 7% and 34% [22] after delivery. Fornell et al. [19] suggest “incontinence once a week or more often” as a measure of incontinence in populations where objective signs are not available on record”. Using this cut-off there is significantly less SUI in the electively operated group (group 3) which is in accordance with previous studies [23, 24]. Sheer et al. [22] who examined women 10 weeks postpartum and used a well-defined control group with no missed injuries of the anal sphincter, noted urinary leakage more often among women with known OASIS. The association between OASIS and SUI remains to be determined but one hypothesis is that extensive soft tissue trauma may also afflict the structures of the urethral supportive mechanisms [25, 26].

In previous studies the sense of vaginal bulge has been shown to correlate with clinically significant prolapse [17]. A correlation between excessive stretching and tearing and POP (pelvic organ prolapse) later in life has been found [25-27]. In our study the sense of bulging was most often reported by the women with a complete OASIS. We found it noteworthy that as many as 4.5% of patients with, what we believe to be smaller lacerations, nevertheless report prolapse symptoms as soon as 12–18 months after delivery. The current classification of vaginal tears may be insufficient, as it focuses on the anal sphincter and perineum only, leaving lacerations in the other compartments of the pelvic floor without thorough description and classification.

Involuntary gas leakage was frequent in both groups 1 and 2 but also afflicted about one third of the women in groups 3 and 4. There are problems with the concept of gas incontinence since passing gas is a physiological function and therefore gas incontinence cannot be defined in the same obvious way as stools incontinence. Our figures are, nevertheless, concurrent with previous studies [16, 28, 29].

It has been shown that anal incontinence after delivery is associated with increasing size of the internal anal sphincter defect [30, 31]. In our study, leakage of liquid stools occurred rather frequently in both groups 1 and 2 (17.7% and 17.0%, respectively) but also occurred among women delivered vaginally with no known OASIS. The explanation to this might be the difficulty of detecting these injuries but also that the mechanisms behind anal incontinence after childbirth are not yet fully understood.

The fact that no one in group 1 reported solid stool incontinence raises the question as to whether the questionnaire did not accurately measure what it was supposed to measure. Perhaps large tears are more easily detected and thereby have a better chance of optimal attention, suturing and postpartum advice. Among women with a partial rupture and moreover, among women with a vaginal delivery with no reported OASIS a fairly large number reported leakage. This might indicate that the diagnosis in some cases had been missed.

Since the incidence of OASIS is used as a measurement of quality of care there might be a disincentive to document these injuries correctly. It is apparent from this study, that symptoms of PFD also occur in women with perineal tears that are considered uncomplicated. We thus suggest that it is necessary not only to report the incidence of OASIS, but also to evaluate the pelvic floor symptoms among women after childbirth. Furthermore, high detection rates may indicate attention and knowledge about the condition and thereby a greater possibility to prevent symptoms of anal incontinence due to missed OASIS [15]. This questionnaire focusing on women's symptoms a year after delivery contributes important information towards achieving this goal, seems to identify expected symptoms with reasonable accuracy and may therefore be utilized as a measurement of quality of care and feedback to obstetrical practices.