| Literature DB >> 20795620 |
Luis M De León-Rodríguez1, Angelo Lubag, D Gomika Udugamasooriya, Bettina Proneth, Rolf A Brekken, Xiankai Sun, Thomas Kodadek, A Dean Sherry.
Abstract
The synthesis of a polylysine dendron containing eight GdDOTA units conjugated to a peptoid dimer known to have a high affinity for the vascular endothelial growth factor receptor 2 (VEGFR2) is described. This simple low molecular weight system with a molecular r(1) relaxivity of ∼48 mM(-1) s(-1) is shown to enhance MR images of tumors grown in mice in vivo.Entities:
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Year: 2010 PMID： 20795620 PMCID： PMC2967214 DOI： 10.1021/ja105563a
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419