Literature DB >> 2079423

Use of the 82Sr/82Rb generator in clinical PET studies.

G B Saha1, R T Go, W J MacIntyre, T H Marwick, A Beachler, J L King, D R Neumann.   

Abstract

The use of the 82Sr/82Rb generator in clinical positron emission tomography (PET) studies of myocardial perfusion has been described. An infusion pump is used to deliver the short-lived 82Rb from the generator to the patient. Various characteristics of the generator and the infusion system are described. The 82Rb yield was 69.8 +/- 13.3% and the 82Sr breakthrough was always less than the limit of 0.02 microCi/mCi 82Rb. The yield of 82Rb increased with the flow rate and the potency of the generator. Patients with coronary artery disease were studied for myocardial perfusion abnormalities by the 82Rb PET technique and images of excellent diagnostic quality were obtained.

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Year:  1990        PMID: 2079423     DOI: 10.1016/0883-2897(90)90023-t

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum B        ISSN: 0883-2897


  2 in total

1.  Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals.

Authors:  Sibaprasad Bhattacharyya; Manish Dixit
Journal:  Dalton Trans       Date:  2011-05-03       Impact factor: 4.390

2.  Limitations of Rb-82 weight-adjusted dosing accuracy at low doses.

Authors:  Jonathan B Moody; Kerri M Hiller; Benjamin C Lee; James R Corbett; Edward P Ficaro; Venkatesh L Murthy
Journal:  J Nucl Cardiol       Date:  2016-05-16       Impact factor: 5.952

  2 in total

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