Literature DB >> 207551

Evidence for the nonhydrophobic interaction of aromatic, nitrogen-containing compounds with the coenzyme binding site of a NAD-linked D-lactate dehydrogenase.

G L Long, J R Cook, W R Ellington.   

Abstract

Quantitative structure activity relationships suggest that the binding of quinoline and phenanthroline analogs to D-lactate dehydrogenase from the barnacle, Balanus nubilus Darwin, does not involve primarily hydrophobic effects. This phenomenon appears to exist also for other lactate dehydrogenases.

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Year:  1978        PMID： 207551     DOI： 10.1007/bf01936962

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Correlation analysis of Baker's studies on enzyme inhibition. 2. Chymotrypsin, trypsin, thymidine phosphorylase, uridine phosphorylase, thymidylate synthetase, cytosine nucleoside deaminase, dihydrofolate reductase, malate dehydrogenase, glutamate dehydrogenase, lactate dehydrogenase, and glyceraldehyde-phosphate dehydrogenase.

Authors:  M Yoshimoto; C Hansch
Journal:  J Med Chem       Date:  1976-01       Impact factor: 7.446

2.  Inhibition of glutamic dehydrogenase by o-phenanthroline and its analogs.

Authors:  K L YIELDING; G M TOMKINS
Journal:  Biochim Biophys Acta       Date:  1962-08-13

3.  Structure-activity relationships in papain-ligand interactions.

Authors:  C Hansch; D F Calef
Journal:  J Org Chem       Date:  1976-04-02       Impact factor: 4.354

4.  The action of chelating agents on human liver aldehyde dehydrogenase.

Authors:  R S Sidhu; A H Blair
Journal:  Biochem J       Date:  1975-11       Impact factor: 3.857

5.  Binding of salicylate in the adenosine-binding pocket of dehydrogenases.

Authors:  R Einarsson; H Eklund; E Zeppezauer; T Boiwe; C I Brändén
Journal:  Eur J Biochem       Date:  1974-11-01

6.  Nitrogen base inhibition of yeast alcohol dehydrogenase.

Authors:  B M Anderson; M L Reynolds; C D Anderson
Journal:  Biochim Biophys Acta       Date:  1966-02-14

7.  "Aromatic" substituent constants for structure-activity correlations.

Authors:  C Hansch; A Leo; S H Unger; K H Kim; D Nikaitani; E J Lien
Journal:  J Med Chem       Date:  1973-11       Impact factor: 7.446

8.  The absence of zinc in the mitochondrial and supernatant forms of malate dehydrogenase.

Authors:  P R Mathewson; F J Yost; J H Harrison
Journal:  Biochim Biophys Acta       Date:  1973-10-10

9.  X-ray investigation of the binding of 1,10-phenanthroline and imidazole to horse-liver alcohol dehydrogenase.

Authors:  T Boiwe; C I Bränden
Journal:  Eur J Biochem       Date:  1977-07-01

10.  Binding of Cibacron blue F3GA to proteins containing the dinucleotide fold.

Authors:  S T Thompson; E Stellwagen
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205
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