Literature DB >> 20740115

Clostridium difficile Infections: What Every Clinician Should Know.

James Yoo, Amy Lee Lightner.   

Abstract

The leading cause of nosocomial enteric infections in the US is a potentially lethal condition that influences the daily care of medical and surgical patients across all specialties. The incidence is increasing because of the emergence of a new virulent strain, the development of antibiotic resistance, and an increase in infection rates within populations once believed to be at low risk. Current strategies for the prevention, diagnosis, and treatment are cited. Transmission can be minimized with the use of gloves and gowns; proper hand washing with soap and water (alcohol-based washes do not prevent transmission); careful use and proper cleaning of shared patient equipment, such as blood-pressure cuffs, thermometers, and stethoscopes; and the use of bactericidal cleaning solutions. Restricted or judicious antibiotic use will also reduce the incidence of Clostridium difficile infections.

Entities:  

Year:  2010        PMID: 20740115      PMCID: PMC2912081          DOI: 10.7812/TPP/10-001

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  41 in total

Review 1.  Pediatric Clostridium difficile: a phantom menace or clinical reality?

Authors:  L V McFarland; S A Brandmarker; S Guandalini
Journal:  J Pediatr Gastroenterol Nutr       Date:  2000-09       Impact factor: 2.839

2.  An epidemic, toxin gene-variant strain of Clostridium difficile.

Authors:  L Clifford McDonald; George E Killgore; Angela Thompson; Robert C Owens; Sophia V Kazakova; Susan P Sambol; Stuart Johnson; Dale N Gerding
Journal:  N Engl J Med       Date:  2005-12-01       Impact factor: 91.245

3.  Nosocomial acquisition of Clostridium difficile infection.

Authors:  L V McFarland; M E Mulligan; R Y Kwok; W E Stamm
Journal:  N Engl J Med       Date:  1989-01-26       Impact factor: 91.245

4.  Metronidazole or vancomycin for Clostridium difficile associated diarrhoea.

Authors:  R S Gordon
Journal:  Lancet       Date:  1983-12-17       Impact factor: 79.321

5.  Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada.

Authors:  Jacques Pepin; Marie-Eve Alary; Louis Valiquette; Evelyne Raiche; Joannie Ruel; Katalin Fulop; Dominique Godin; Claude Bourassa
Journal:  Clin Infect Dis       Date:  2005-04-25       Impact factor: 9.079

6.  Treatment with monoclonal antibodies against Clostridium difficile toxins.

Authors:  Israel Lowy; Deborah C Molrine; Brett A Leav; Barbra M Blair; Roger Baxter; Dale N Gerding; Geoffrey Nichol; William D Thomas; Mark Leney; Susan Sloan; Catherine A Hay; Donna M Ambrosino
Journal:  N Engl J Med       Date:  2010-01-21       Impact factor: 91.245

7.  Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease.

Authors:  Lynne V McFarland; Gary W Elmer; Christina M Surawicz
Journal:  Am J Gastroenterol       Date:  2002-07       Impact factor: 10.864

8.  Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial.

Authors:  S Johnson; S R Homann; K M Bettin; J N Quick; C R Clabots; L R Peterson; D N Gerding
Journal:  Ann Intern Med       Date:  1992-08-15       Impact factor: 25.391

9.  Impact of Clostridium difficile on inflammatory bowel disease.

Authors:  Mazen Issa; Aravind Vijayapal; Mary Beth Graham; Dawn B Beaulieu; Mary F Otterson; Sarah Lundeen; Susan Skaros; Lydia R Weber; Richard A Komorowski; Josh F Knox; Jeanne Emmons; Jasmohan S Bajaj; David G Binion
Journal:  Clin Gastroenterol Hepatol       Date:  2007-03       Impact factor: 11.382

10.  Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis.

Authors:  K H Kim; R Fekety; D H Batts; D Brown; M Cudmore; J Silva; D Waters
Journal:  J Infect Dis       Date:  1981-01       Impact factor: 5.226

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  5 in total

1.  Comparison of five assays for detection of Clostridium difficile toxin.

Authors:  Kimberle C Chapin; Roberta A Dickenson; Fongman Wu; Sarah B Andrea
Journal:  J Mol Diagn       Date:  2011-04-29       Impact factor: 5.568

2.  Association of tcdA+/tcdB+ Clostridium difficile Genotype with Emergence of Multidrug-Resistant Strains Conferring Metronidazole Resistant Phenotype.

Authors:  Farahnaz-Sadat Shayganmehr; Masoud Alebouyeh; Masoumeh Azimirad; Mohammad Mehdi Aslani; Mohammad Reza Zali
Journal:  Iran Biomed J       Date:  2015-06-06

3.  Prevalence of Clostridium difficile and its toxigenic genotype in beef samples in west of Iran.

Authors:  Malihe Kheradmand; Somayeh Jalilian; Amirhooshang Alvandi; Ramin Abiri
Journal:  Iran J Microbiol       Date:  2017-06

4.  Fast and near-optimal monitoring for healthcare acquired infection outbreaks.

Authors:  Bijaya Adhikari; Bryan Lewis; Anil Vullikanti; José Mauricio Jiménez; B Aditya Prakash
Journal:  PLoS Comput Biol       Date:  2019-09-16       Impact factor: 4.475

5.  Significance of Clostridium difficile in community-acquired diarrhea in a tertiary care center in Lebanon.

Authors:  Reem Al Assaad; Alik Dakessian; Rana Bachir; Abdul Rahman Bizri; Mazen El Sayed
Journal:  Sci Rep       Date:  2020-03-30       Impact factor: 4.379

  5 in total

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