| Literature DB >> 20737548 |
Valerie Voon1, Tracy R Butler, Vindhya Ekanayake, Cecile Gallea, Rezvan Ameli, Dennis L Murphy, Mark Hallett.
Abstract
Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction.Entities:
Mesh:
Year: 2010 PMID: 20737548 PMCID: PMC4082988 DOI: 10.1002/mds.23250
Source DB: PubMed Journal: Mov Disord ISSN: 0885-3185 Impact factor: 10.338