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Literature DB >> 20736437

Opioid-induced preconditioning is dependent on caveolin-3 expression.

Yasuo M Tsutsumi¹, Yoshitaka Kawaraguchi, Ingrid R Niesman, Hemal H Patel, David M Roth.

Abstract

We tested the hypothesis that caveolin-3 (Cav-3) is essential for opioid-induced preconditioning in vivo. Cav-3 overexpressing mice, Cav-3 knockout mice, and controls were exposed to myocardial ischemia/reperfusion (I/R) in the presence of SNC-121 (SNC), a δ-selective opioid agonist, or naloxone, a nonselective opioid antagonist. Controls were protected from I/R injury by SNC. No protection was produced by SNC in Cav-3 knockout mice. Cav-3 overexpressing mice showed innate protection from I/R compared with controls that was abolished by naloxone. Our results show that opioid-induced preconditioning is dependent on Cav-3 expression and that endogenous protection in Cav-3 overexpressing mice is opioid dependent.

Entities: Chemical Disease Gene Species

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Year: 2010 PMID： 20736437 PMCID： PMC3098574 DOI： 10.1213/ANE.0b013e3181f3351a

Source DB: PubMed Journal: Anesth Analg ISSN： 0003-2999 Impact factor: 5.108

24 in total

1. G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes.

Authors: Brian P Head; Hemal H Patel; David M Roth; N Chin Lai; Ingrid R Niesman; Marilyn G Farquhar; Paul A Insel
Journal: J Biol Chem Date: 2005-06-16 Impact factor: 5.157

2. Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1.

Authors: Hemal H Patel; Yasuo M Tsutsumi; Brian P Head; Ingrid R Niesman; Michelle Jennings; Yousuke Horikawa; Diane Huang; Ana L Moreno; Piyush M Patel; Paul A Insel; David M Roth
Journal: FASEB J Date: 2007-02-01 Impact factor: 5.191

3. Localization of preproenkephalin mRNA in rat heart: selective gene expression in left ventricular myocardium.

Authors: J Weil; T Eschenhagen; G Fleige; C Mittmann; E Orthey; H Scholz
Journal: Am J Physiol Date: 1998-08

4. Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors.

Authors: J E Schultz; A K Hsu; G J Gross
Journal: Circulation Date: 1998-04-07 Impact factor: 29.690

5. Protection of adult rat cardiac myocytes from ischemic cell death: role of caveolar microdomains and delta-opioid receptors.

Authors: Hemal H Patel; Brian P Head; Heidi N Petersen; Ingrid R Niesman; Diane Huang; Garrett J Gross; Paul A Insel; David M Roth
Journal: Am J Physiol Heart Circ Physiol Date: 2006-02-24 Impact factor: 4.733

6. Effects of naloxone on myocardial ischemic preconditioning in humans.

Authors: F Tomai; F Crea; A Gaspardone; F Versaci; A S Ghini; C Ferri; G Desideri; L Chiariello; P A Gioffré
Journal: J Am Coll Cardiol Date: 1999-06 Impact factor: 24.094

Review 7. The endogenous cardiac cannabinoid system: a new protective mechanism against myocardial ischemia.

Authors: D Lamontagne; P Lépicier; C Lagneux; J F Bouchard
Journal: Arch Mal Coeur Vaiss Date: 2006-03

8. Role of nitric oxide, muscarinic receptors, and the ATP-sensitive K+ channel in mediating the effects of acetylcholine to mimic preconditioning in dogs.

Authors: Z Yao; G J Gross
Journal: Circ Res Date: 1993-12 Impact factor: 17.367

9. Reactive oxygen species trigger ischemic and pharmacological postconditioning: in vivo and in vitro characterization.

Authors: Yasuo M Tsutsumi; Takaakira Yokoyama; Yousuke Horikawa; David M Roth; Hemal H Patel
Journal: Life Sci Date: 2007-09-09 Impact factor: 5.037

10. Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts.

Authors: J E Schultz; E Rose; Z Yao; G J Gross
Journal: Am J Physiol Date: 1995-05

17 in total

Review 1. Sarcolemmal dependence of cardiac protection and stress-resistance: roles in aged or diseased hearts.

Authors: Louise E See Hoe; Lauren T May; John P Headrick; Jason N Peart
Journal: Br J Pharmacol Date: 2016-09-09 Impact factor: 8.739

2. Sarcolemmal cholesterol and caveolin-3 dependence of cardiac function, ischemic tolerance, and opioidergic cardioprotection.

Authors: Louise E See Hoe; Jan M Schilling; Emiri Tarbit; Can J Kiessling; Anna R Busija; Ingrid R Niesman; Eugene Du Toit; Kevin J Ashton; David M Roth; John P Headrick; Hemal H Patel; Jason N Peart
Journal: Am J Physiol Heart Circ Physiol Date: 2014-07-25 Impact factor: 4.733

Review 3. Caveolins in cardioprotection - translatability and mechanisms.

Authors: Jan M Schilling; David M Roth; Hemal H Patel
Journal: Br J Pharmacol Date: 2015-01-13 Impact factor: 8.739

4. Geranylgeranylacetone and volatile anesthetic-induced cardiac protection synergism is dependent on caveolae and caveolin-3.

Authors: Yasuo M Tsutsumi; Rie Tsutsumi; Yousuke T Horikawa; Yoko Sakai; Eisuke Hamaguchi; Hiroshi Kitahata; Asuka Kasai; Noriko Kambe; Katsuya Tanaka
Journal: J Anesth Date: 2014-03-15 Impact factor: 2.078

Review 5. Opioid-induced cardioprotection.

Authors: Katsuya Tanaka; Judy R Kersten; Matthias L Riess
Journal: Curr Pharm Des Date: 2014 Impact factor: 3.116