Literature DB >> 25377989

Caveolins in cardioprotection - translatability and mechanisms.

Jan M Schilling1, David M Roth, Hemal H Patel.   

Abstract

Translation of preclinical treatments for ischaemia-reperfusion injury into clinical therapies has been limited by a number of factors. This review will focus on a single mode of cardiac protection related to a membrane scaffolding protein, caveolin, which regulates protective signalling as well as myocyte ultrastructure in the setting of ischaemic stress. Factors that have limited the clinical translation of protection will be considered specifically in terms of signalling and structural defects. The potential of caveolin to overcome barriers to protection with the ultimate hope of clinical translation will be discussed.
© 2014 The British Pharmacological Society.

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Year:  2015        PMID： 25377989      PMCID： PMC4386985          DOI： 10.1111/bph.13009

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  187 in total

1.  Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener.

Authors:  A Jahangir; C Ozcan; E L Holmuhamedov; A Terzic
Journal:  Mech Ageing Dev       Date:  2001-07-31       Impact factor: 5.432

Review 2.  Caveolins: structure and function in signal transduction.

Authors:  Wanda M Krajewska; Izabela Masłowska
Journal:  Cell Mol Biol Lett       Date:  2004       Impact factor: 5.787

3.  Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry.

Authors:  Jan M Schilling; Weihua Cui; Joseph C Godoy; Victoria B Risbrough; Ingrid R Niesman; David M Roth; Piyush M Patel; John C Drummond; Hemal H Patel; Alice E Zemljic-Harpf; Brian P Head
Journal:  Behav Brain Res       Date:  2014-03-19       Impact factor: 3.332

4.  Transcellular transport of CCL2 across brain microvascular endothelial cells.

Authors:  Shujun Ge; Li Song; David R Serwanski; William A Kuziel; Joel S Pachter
Journal:  J Neurochem       Date:  2008-03       Impact factor: 5.372

5.  Intermittent hypoxia exposure prevents mtDNA deletion and mitochondrial structure damage produced by ischemia/reperfusion injury.

Authors:  N Zhong; Y Zhang; H F Zhu; Z N Zhou
Journal:  Sheng Li Xue Bao       Date:  2000-10

6.  Insulin resistance in skeletal muscles of caveolin-3-null mice.

Authors:  Jin Oshikawa; Koji Otsu; Yoshiyuki Toya; Takashi Tsunematsu; Raleigh Hankins; Jun-ichi Kawabe; Susumu Minamisawa; Satoshi Umemura; Yasuko Hagiwara; Yoshihiro Ishikawa
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

7.  Regulation of plasma long-chain fatty acid oxidation in relation to uptake in human skeletal muscle during exercise.

Authors:  Carsten Roepstorff; Bodil Vistisen; Kirstine Roepstorff; Bente Kiens
Journal:  Am J Physiol Endocrinol Metab       Date:  2004-06-08       Impact factor: 4.310

8.  A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization.

Authors:  Libin Liu; Paul F Pilch
Journal:  J Biol Chem       Date:  2007-12-03       Impact factor: 5.157

9.  The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

Authors:  Stephen P H Alexander; Helen E Benson; Elena Faccenda; Adam J Pawson; Joanna L Sharman; Michael Spedding; John A Peters; Anthony J Harmar
Journal:  Br J Pharmacol       Date:  2013-12       Impact factor: 8.739

10.  Localization of inositol 1,4,5-trisphosphate receptor-like protein in plasmalemmal caveolae.

Authors:  T Fujimoto; S Nakade; A Miyawaki; K Mikoshiba; K Ogawa
Journal:  J Cell Biol       Date:  1992-12       Impact factor: 10.539
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  12 in total

Review 1.  Sarcolemmal dependence of cardiac protection and stress-resistance: roles in aged or diseased hearts.

Authors:  Louise E See Hoe; Lauren T May; John P Headrick; Jason N Peart
Journal:  Br J Pharmacol       Date:  2016-09-09       Impact factor: 8.739

2.  'Conditioning the heart' - lessons we have learned from the past and future perspectives for new and old conditioning 'drugs'.

Authors:  Nina C Weber
Journal:  Br J Pharmacol       Date:  2015-04       Impact factor: 8.739

Review 3.  Caveolins and caveolae in ocular physiology and pathophysiology.

Authors:  Xiaowu Gu; Alaina M Reagan; Mark E McClellan; Michael H Elliott
Journal:  Prog Retin Eye Res       Date:  2016-09-21       Impact factor: 21.198

Review 4.  Caveolins and cavins in the trafficking, maturation, and degradation of caveolae: implications for cell physiology.

Authors:  Anna R Busija; Hemal H Patel; Paul A Insel
Journal:  Am J Physiol Cell Physiol       Date:  2017-01-25       Impact factor: 4.249

Review 5.  New Therapeutic Options for Type 2 Diabetes Mellitus and Their Impact Against Ischemic Heart Disease.

Authors:  Malak Almutairi; Jordan S F Chan; John R Ussher
Journal:  Front Physiol       Date:  2022-06-27       Impact factor: 4.755

6.  Protective role of cardiac-specific overexpression of caveolin-3 in cirrhotic cardiomyopathy.

Authors:  So Yeon Kim; Kang Ho Kim; Jan M Schilling; Joseph Leem; Mehul Dhanani; Brian P Head; David M Roth; Alice E Zemljic-Harpf; Hemal H Patel
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2020-01-21       Impact factor: 4.052

7.  The Effects of Aging on the Regulation of T-Tubular ICa by Caveolin in Mouse Ventricular Myocytes.

Authors:  Cherrie H T Kong; Simon M Bryant; Judy J Watson; Hanne C Gadeberg; David M Roth; Hemal H Patel; Mark B Cannell; Clive H Orchard; Andrew F James
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2018-05-09       Impact factor: 6.053

Review 8.  Myocyte membrane and microdomain modifications in diabetes: determinants of ischemic tolerance and cardioprotection.

Authors:  Jake Russell; Eugene F Du Toit; Jason N Peart; Hemal H Patel; John P Headrick
Journal:  Cardiovasc Diabetol       Date:  2017-12-04       Impact factor: 9.951

Review 9.  Gaseous mediators: an updated review on the effects of helium beyond blowing up balloons.

Authors:  Nina C Weber; Benedikt Preckel
Journal:  Intensive Care Med Exp       Date:  2019-12-19

Review 10.  Conditioning-induced cardioprotection: Aging as a confounding factor.

Authors:  Puneet Kaur Randhawa; Anjana Bali; Jasleen Kaur Virdi; Amteshwar Singh Jaggi
Journal:  Korean J Physiol Pharmacol       Date:  2018-08-27       Impact factor: 2.016
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