Literature DB >> 20732763

Assessment of out-of-field doses in radiotherapy of brain lesions in children.

Michael L Taylor1, Tomas Kron, Rick D Franich.   

Abstract

PURPOSE: To characterize the out-of-field doses in pediatric radiotherapy and to identify simple methods by which out-of-field dose might be minimized, with a view to reducing the risk of secondary cancers. METHODS AND MATERIALS: With the aim of characterizing the peripheral doses under different treatment conditions, the dose measurements in an anthropomorphic child phantom were taken in various organs and critical structures outside the primary field using thermoluminescent dosimetry. The doses from a Varian 600C and Varian Trilogy linear accelerator, both at 6 MV, were investigated.
RESULTS: Larger field sizes have been shown to result in greater peripheral doses close to the primary beam, with the difference becoming less significant at large distances, indicating that most of out-of-field doses result from head leakage and collimator scatter>40 cm from the primary field. The use of lead shields has been shown to reduce the absorbed dose resulting from leakage. Aligning the craniocaudal axis of the patient with the x-plane of the collimator resulted in a dose reduction of 40%, for both machines. Out-of-field doses from the Varian Trilogy were shown to be approximately 40% greater than those from the 600C linear accelerator, despite being operated at the same energy.
CONCLUSION: Out-of-field doses to pediatric patients can be minimized by using simple treatment options, such as using the single-energy mode linear accelerator rather than the multimode, orienting the couch and collimator such that the patient lies along the x-plane and avoiding fields directed along the trunk of the body.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20732763     DOI: 10.1016/j.ijrobp.2010.04.064

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  4 in total

1.  Consideration of the radiation dose delivered away from the treatment field to patients in radiotherapy.

Authors:  Michael L Taylor; Tomas Kron
Journal:  J Med Phys       Date:  2011-04

2.  The influence of field size on stopping-power ratios in- and out-of-field: quantitative data for the BrainLAB m3 micro-multileaf collimator.

Authors:  Michael Taylor; Tanya Kairn; Tomas Kron; Leon Dunn; Peter N Johnston; Rick D Franich
Journal:  J Appl Clin Med Phys       Date:  2012-11-08       Impact factor: 2.102

3.  Accuracy and sources of error of out-of field dose calculations by a commercial treatment planning system for intensity-modulated radiation therapy treatments.

Authors:  Jessie Y Huang; David S Followill; Xin A Wang; Stephen F Kry
Journal:  J Appl Clin Med Phys       Date:  2013-03-04       Impact factor: 2.102

4.  Out-of-field dose in stereotactic radiotherapy for paediatric patients.

Authors:  Lachlan Garrett; Nicholas Hardcastle; Adam Yeo; Peta Lonski; Rick Franich; Tomas Kron
Journal:  Phys Imaging Radiat Oncol       Date:  2021-06-04
  4 in total

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