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Literature DB >> 20731883

Kinesin-14: the roots of reversal.

Abstract

Kinesin-14 motor proteins step towards microtubule minus ends, in the opposite direction to other kinesins. Work on the still-enigmatic kinesin-14 mechanism published in BMC Structural Biology shows that the carboxyl terminus of the motor head undergoes a dock-undock cycle, like that of plus-end-directed kinesins.

Entities: Chemical Disease Gene Mutation Species

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Year: 2010 PMID： 20731883 PMCID： PMC2922096 DOI： 10.1186/1741-7007-8-107

Source DB: PubMed Journal: BMC Biol ISSN： 1741-7007 Impact factor: 7.431

13 in total

Review 1. The way things move: looking under the hood of molecular motor proteins.

Authors: R D Vale; R A Milligan
Journal: Science Date: 2000-04-07 Impact factor: 47.728

2. A mutant of the motor protein kinesin that moves in both directions on microtubules.

Authors: S A Endow; H Higuchi
Journal: Nature Date: 2000-08-24 Impact factor: 49.962

3. Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd.

Authors: Mikyung Yun; C Eric Bronner; Cheon-Gil Park; Sun-Shin Cha; Hee-Won Park; Sharyn A Endow
Journal: EMBO J Date: 2003-10-15 Impact factor: 11.598

4. The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor.

Authors: H B McDonald; R J Stewart; L S Goldstein
Journal: Cell Date: 1990-12-21 Impact factor: 41.582

5. Motor proteins: kinesin drives with an underhead cam.

Authors: Matthew J Lang; Wonmuk Hwang
Journal: Curr Biol Date: 2010-05-11 Impact factor: 10.834

6. Kinesin's cover-neck bundle folds forward to generate force.

Authors: Ahmad S Khalil; David C Appleyard; Anna K Labno; Adrien Georges; Martin Karplus; Angela M Belcher; Wonmuk Hwang; Matthew J Lang
Journal: Proc Natl Acad Sci U S A Date: 2008-12-01 Impact factor: 11.205

7. Determinants of kinesin motor polarity.

Authors: S A Endow; K W Waligora
Journal: Science Date: 1998-08-21 Impact factor: 47.728

8. The Drosophila claret segregation protein is a minus-end directed motor molecule.

Authors: R A Walker; E D Salmon; S A Endow
Journal: Nature Date: 1990-10-25 Impact factor: 49.962

9. Large conformational changes in a kinesin motor catalyzed by interaction with microtubules.

Authors: Keiko Hirose; Erika Akimaru; Toshihiko Akiba; Sharyn A Endow; Linda A Amos
Journal: Mol Cell Date: 2006-09-15 Impact factor: 17.970

10. A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd.

Authors: Nicholas F Endres; Craig Yoshioka; Ronald A Milligan; Ronald D Vale
Journal: Nature Date: 2005-12-28 Impact factor: 49.962

9 in total

1. Ensemble velocity of non-processive molecular motors with multiple chemical states.

Authors: Andrej Vilfan
Journal: Interface Focus Date: 2014-12-06 Impact factor: 3.906

2. Working stroke of the kinesin-14, ncd, comprises two substeps of different direction.

Authors: Bert Nitzsche; Elzbieta Dudek; Lukasz Hajdo; Andrzej A Kasprzak; Andrej Vilfan; Stefan Diez
Journal: Proc Natl Acad Sci U S A Date: 2016-10-11 Impact factor: 11.205

Review 3. Microtubule-based force generation.

Authors: Ian A Kent; Tanmay P Lele
Journal: Wiley Interdiscip Rev Nanomed Nanobiotechnol Date: 2016-08-25