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Literature DB >> 20728355

Identification and optimization of substituted 5-aminopyrazoles as potent and selective adenosine A1 receptor antagonists.

Abstract

Potent and selective adenosine A(1) receptor antagonists were disclosed. SAR and pharmacological profile of selected compounds were discussed.

Entities: Chemical Gene

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

2 in total

Authors: Paula Ruiz-Castillo; Stephen L Buchwald
Journal: Chem Rev Date: 2016-09-30 Impact factor: 60.622

Authors: Ju Liu; Zhi-Qiang Cai; Yang Wang; Chun-Yan Li; Li-Feng Xu
Journal: Acta Crystallogr Sect E Struct Rep Online Date: 2012-03-24

2 in total