| Literature DB >> 20728319 |
Jianfeng Shen1, Min Shi, Bo Yan, Hongwei Ma, Na Li, Yizhe Hu, Mingxin Ye.
Abstract
In this paper, graphene oxide nanosheets (GOS) are functionalized by bovine serum albumin (BSA) via diimide-activated amidation under ambient conditions. The obtained GOS-BSA conjugate is highly water-soluble. Results of atomic force microscopy (AFM), Raman spectra and Fourier transform infrared spectroscopy analysis confirm that GOS-BSA conjugate contains both GOS and BSA protein. AFM image shows that GOS are fully exfoliated. Results of cyclic volatammograms show that the protein in the GOS-BSA conjugate retains its bioactivity. The present method may also provide a way to synthesize graphene-based composites with other biomolecules.Entities:
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Year: 2010 PMID: 20728319 DOI: 10.1016/j.colsurfb.2010.07.035
Source DB: PubMed Journal: Colloids Surf B Biointerfaces ISSN: 0927-7765 Impact factor: 5.268