| Literature DB >> 20723753 |
Sjoerd van Deventer1, Jacques Neefjes.
Abstract
Immune cells and cells activated by the inflammatory cytokine interferon express variant proteasomes called immunoproteasomes that are characterized by unique catalytic subunits. Seifert et al. (2010) now show in mouse models of inflammatory disease that immunoproteasomes help prevent the accumulation of harmful protein aggregates. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
Year: 2010 PMID: 20723753 DOI: 10.1016/j.cell.2010.08.002
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582