Literature DB >> 20722782

Inflatable penile prosthesis placement in men with Peyronie's disease and drug-resistant erectile dysfunction: A single-center study.

Laurence A Levine1, Jonas Benson, Christopher Hoover.   

Abstract

INTRODUCTION: Erectile dysfunction (ED) frequently accompanies Peyronie's disease (PD) and changes the therapeutic approach. AIM: To evaluate a single-center experience with inflatable penile prostheses (IPP) in men with medication refractory ED and PD.
METHODS: Ninety men underwent placement of an IPP with straightening maneuvers as necessary to address their deformity and ED. MAIN OUTCOME MEASURES: Preoperative assessment included International Index of Erectile Function-erectile function domain (IIEF-EF) and duplex ultrasound to confirm ED and measure erect deformity. Postoperative assessment included a modified Erectile Dysfunction Index of Treatment Satisfaction (EDITS) questionnaire, as well as office visits at 1, 6, and every 12 months thereafter.
RESULTS: Complete chart review was performed with mean follow-up of 49 months. Mean preoperative IIEF-EF score was 11. Full rigidity was not obtained in any patient during duplex ultrasound. Mean curvature at maximum erection was 53°. There were seven mechanical failures requiring device replacement, two revision surgeries for pump or reservoir malposition, one infected device, and two corporoplasties for distal tunica erosion. Postoperative office assessment revealed a functionally straight (i.e., <20°) erect penis and a properly positioned as well as operational device in all patients. The modified EDITS questionnaire was returned by 56 (62%). Overall, 84% of patients were satisfied with their outcome, yet only 73% were satisfied with their straightness. Patient perceived postoperative curvature correction stabilized quickly and was complete by 3 months in 84% of patients. Satisfaction with ease of inflation, deflation, and concealability was 84%, 71%, and 91%, respectively. Coital activity was reported by 91% of men in this group.
CONCLUSION: In men with PD and ED, IPP placement allowed reliable and satisfactory coitus for the great majority of men. Mechanical failure was 7%. Men with PD undergoing IPP placement should be counseled regarding potential penile length loss and residual curvature, neither of which appeared to interfere with coitus but may reduce satisfaction.
© 2010 International Society for Sexual Medicine.

Entities:  

Mesh:

Year:  2010        PMID: 20722782     DOI: 10.1111/j.1743-6109.2010.01971.x

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  26 in total

Review 1.  A practical overview of considerations for penile prosthesis placement.

Authors:  Landon Trost; Philip Wanzek; George Bailey
Journal:  Nat Rev Urol       Date:  2015-12-01       Impact factor: 14.432

Review 2.  Treatment of Peyronie's disease: 2012 update.

Authors:  Ege Can Serefoglu; Wayne J G Hellstrom
Journal:  Curr Urol Rep       Date:  2011-12       Impact factor: 3.092

3.  Penile prosthesis implantation and tunica albuginea incision without grafting in the treatment of Peyronie's disease with erectile dysfunction.

Authors:  Miroslav L Djordjevic; Vladimir Kojovic
Journal:  Asian J Androl       Date:  2013-02-25       Impact factor: 3.285

Review 4.  Strategies for penile prosthesis placement in Peyronie's disease and corporal fibrosis.

Authors:  Faysal A Yafi; Premsant Sangkum; Ian Ross McCaslin; Wayne J G Hellstrom
Journal:  Curr Urol Rep       Date:  2015-04       Impact factor: 3.092

Review 5.  A Contemporary Evaluation of Peyronie's Disease During Penile Prosthesis Placement: MOST, MUST, and More.

Authors:  Jonathan Nicholas Warner
Journal:  Curr Urol Rep       Date:  2019-01-30       Impact factor: 3.092

6.  Use of a microdebrider for corporeal excavation and penile prosthesis implantation in men with severely fibrosed corpora cavernosa: a new minimal invasive surgical technique.

Authors:  İbrahim Halil Bozkurt; Tarık Yonguç; Özgü Aydoğdu; Tansu Değirmenci; Murat Arslan; Süleyman Minareci
Journal:  Turk J Urol       Date:  2015-09

Review 7.  2013-2014 updates in Peyronie's disease management.

Authors:  Benjamin A Sherer; Krishnan Warrior; Laurence A Levine
Journal:  Curr Urol Rep       Date:  2014-12       Impact factor: 3.092

Review 8.  Peyronie's Disease: Intralesional Therapy and Surgical Intervention.

Authors:  Louis A Aliperti; Akanksha Mehta
Journal:  Curr Urol Rep       Date:  2016-09       Impact factor: 3.092

Review 9.  Current management of penile implant infections, device reliability, and optimizing cosmetic outcome.

Authors:  John J Mulcahy; Andrew Kramer; William O Brant; Justin L Parker; Paul E Perito; Jeremy B Myers; Richard Bryson; Meagan Dunne
Journal:  Curr Urol Rep       Date:  2014-06       Impact factor: 3.092

Review 10.  Surgery for Peyronie's disease.

Authors:  Laurence A Levine; Stephen M Larsen
Journal:  Asian J Androl       Date:  2012-11-26       Impact factor: 3.285

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