Literature DB >> 20717628

A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.

Kathleen C A Garber1, Kittikhun Wangkanont, Erin E Carlson, Laura L Kiessling.   

Abstract

Shikimic acid can be transformed into monovalent and multivalent glycomimetics that target different members of the C-type lectin class, including DC-SIGN, a dendritic cell lectin that facilitates HIV transmission.

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Year:  2010        PMID： 20717628      PMCID： PMC3005762          DOI： 10.1039/c0cc00830c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  39 in total

1.  Control of multivalent interactions by binding epitope density.

Authors:  Christopher W Cairo; Jason E Gestwicki; Motomu Kanai; Laura L Kiessling
Journal:  J Am Chem Soc       Date:  2002-02-27       Impact factor: 15.419

2.  Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity.

Authors:  D H Slee; S J Romano; J Yu; T N Nguyen; J K John; N K Raheja; F U Axe; T K Jones; W C Ripka
Journal:  J Med Chem       Date:  2001-06-21       Impact factor: 7.446

Review 3.  Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.

Authors:  Neelu Kaila; Bert E Thomas
Journal:  Med Res Rev       Date:  2002-11       Impact factor: 12.944

4.  Synthesis and mannose receptor-mediated uptake of clustered glycomimetics by human dendritic cells: effect of charge.

Authors:  Gerhild Angyalosi; Cyrille Grandjean; Mélanie Lamirand; Claude Auriault; Hélène Gras-Masse; Oleg Melnyk
Journal:  Bioorg Med Chem Lett       Date:  2002-10-07       Impact factor: 2.823

5.  Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate-Mediated Biological Recognition.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  1999-08       Impact factor: 15.336

6.  Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation.

Authors:  Michael P Schön; Thomas Krahn; Margarete Schön; Maria-L Rodriguez; Horst Antonicek; Jeanette E Schultz; Ralf J Ludwig; Thomas M Zollner; Erwin Bischoff; Klaus-D Bremm; Matthias Schramm; Kerstin Henninger; Roland Kaufmann; Harald P M Gollnick; Christina M Parker; W-Henning Boehncke
Journal:  Nat Med       Date:  2002-04       Impact factor: 53.440

7.  A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR. Subunit organization and binding to multivalent ligands.

Authors:  D A Mitchell; A J Fadden; K Drickamer
Journal:  J Biol Chem       Date:  2001-05-30       Impact factor: 5.157

8.  Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.

Authors:  Kenneth K-S Ng; Anand R Kolatkar; Shaun Park-Snyder; Hadar Feinberg; Damon A Clark; Kurt Drickamer; William I Weis
Journal:  J Biol Chem       Date:  2002-02-15       Impact factor: 5.157

9.  Inhibition of P-selectin specific cell adhesion by a low molecular weight, non-carbohydrate compound, KF38789.

Authors:  S Ohta; Y Inujima; M Abe; Y Uosaki; S Sato; I Miki
Journal:  Inflamm Res       Date:  2001-11       Impact factor: 4.575

10.  Hydroaromatic equilibration during biosynthesis of shikimic acid.

Authors:  D R Knop; K M Draths; S S Chandran; J L Barker; R von Daeniken; W Weber; J W Frost
Journal:  J Am Chem Soc       Date:  2001-10-24       Impact factor: 15.419
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  10 in total

1.  Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid.

Authors:  Joseph C Grim; Kathleen C A Garber; Laura L Kiessling
Journal:  Org Lett       Date:  2011-06-28       Impact factor: 6.005

2.  Quinoxalinone Inhibitors of the Lectin DC-SIGN.

Authors:  Shane L Mangold; Lynne R Prost; Laura L Kiessling
Journal:  Chem Sci       Date:  2011-11-24       Impact factor: 9.825

3.  Antigen structure affects cellular routing through DC-SIGN.

Authors:  Cassie M Jarvis; Daniel B Zwick; Joseph C Grim; Mohammad Murshid Alam; Lynne R Prost; Jaye C Gardiner; Soyeong Park; Laraine L Zimdars; Nathan M Sherer; Laura L Kiessling
Journal:  Proc Natl Acad Sci U S A       Date:  2019-07-03       Impact factor: 11.205

4.  Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists.

Authors:  Lynne R Prost; Joseph C Grim; Marco Tonelli; Laura L Kiessling
Journal:  ACS Chem Biol       Date:  2012-07-19       Impact factor: 5.100

Review 5.  Glycopolymer probes of signal transduction.

Authors:  Laura L Kiessling; Joseph C Grim
Journal:  Chem Soc Rev       Date:  2013-04-18       Impact factor: 54.564

6.  Design, synthesis and activity evaluation of mannose-based DC-SIGN antagonists.

Authors:  Nataša Obermajer; Sara Sattin; Cinzia Colombo; Michela Bruno; Urban Svajger; Marko Anderluh; Anna Bernardi
Journal:  Mol Divers       Date:  2010-11-14       Impact factor: 2.943

7.  Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins.

Authors:  Sakonwan Kuhaudomlarp; Eike Siebs; Elena Shanina; Jérémie Topin; Ines Joachim; Priscila da Silva Figueiredo Celestino Gomes; Annabelle Varrot; Didier Rognan; Christoph Rademacher; Anne Imberty; Alexander Titz
Journal:  Angew Chem Int Ed Engl       Date:  2021-03-03       Impact factor: 15.336

Review 8.  Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN.

Authors:  Jonathan Cramer
Journal:  RSC Med Chem       Date:  2021-09-16

9.  A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN.

Authors:  Robert Wawrzinek; Eike-Christian Wamhoff; Jonathan Lefebre; Mareike Rentzsch; Gunnar Bachem; Gary Domeniconi; Jessica Schulze; Felix F Fuchsberger; Hengxi Zhang; Carlos Modenutti; Lennart Schnirch; Marcelo A Marti; Oliver Schwardt; Maria Bräutigam; Mónica Guberman; Dirk Hauck; Peter H Seeberger; Oliver Seitz; Alexander Titz; Beat Ernst; Christoph Rademacher
Journal:  J Am Chem Soc       Date:  2021-11-08       Impact factor: 15.419

Review 10.  Molecular Recognition in C-Type Lectins: The Cases of DC-SIGN, Langerin, MGL, and L-Sectin.

Authors:  Pablo Valverde; J Daniel Martínez; F Javier Cañada; Ana Ardá; Jesús Jiménez-Barbero
Journal:  Chembiochem       Date:  2020-07-02       Impact factor: 3.461
  10 in total

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