| Literature DB >> 12217363 |
Gerhild Angyalosi1, Cyrille Grandjean, Mélanie Lamirand, Claude Auriault, Hélène Gras-Masse, Oleg Melnyk.
Abstract
Effect of charge and shape of multivalent lysine-based cluster glycomimetics on their mannose receptor-mediated uptake by human dendritic cells has been evaluated: The capture is strongly affected by the shape of the ligands. The effect of charge is less pronounced although positive charges on the ligands seem to favor non-specific endocytosis capture.Entities:
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Year: 2002 PMID： 12217363 DOI： 10.1016/s0960-894x(02)00486-9
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823