Literature DB >> 20714183

The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy.

Thomas Klink1, Gunda Kann, Patrick Ellinger, Janine Klink, Franz Grehn, Rainer Guthoff.   

Abstract

BACKGROUND: the Wuerzburg bleb classification score (WBCS) aims at an objective and standardized assessment of the developing filtering bleb after trabeculectomy, in order to detect and treat bleb scarring at the earliest possible stage of development. The purpose of this retrospective study was to evaluate the prognostic value of the early postoperative WBCS for the long-term outcome of trabeculectomy.
METHODS: the WBCS is a grading system for clinical bleb morphology. It evaluates the following parameters: vascularization, corkscrew vessels, encapsulation and microcysts. The WBCS of 113 eyes of 113 consecutive patients after trabeculectomy was determined 1 day, 1 and 2 weeks, 3, 6 and 12 months after surgery. Complete success was defined as an intra-ocular pressure (IOP) <21 mm Hg and >20% pressure reduction without glaucoma medication after 1 year.
RESULTS: a complete success rate of 73.9% and a qualified success rate of 82.4% were achieved 1 year after surgery. The average total bleb score during follow-up in the success group was always higher than in the failure group, but there was no statistically significant difference at any time. The bleb average score for eyes with an IOP of ≤ 12 mm Hg after 2 weeks was significantly higher (p = 0.005) than for eyes with an IOP ≥ 13 mm Hg at the end of follow-up.
CONCLUSION: patients with a higher early WBCS postoperatively had a significantly lower IOP 1 year after surgery. However, the study could not reveal a certain prognostic value of the early total bleb score using the WBCS for the long-term complete success of trabeculectomy. 2010 S. Karger AG, Basel.

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Year:  2010        PMID: 20714183     DOI: 10.1159/000314717

Source DB:  PubMed          Journal:  Ophthalmologica        ISSN: 0030-3755            Impact factor:   3.250


  10 in total

1.  Long-term follow-up of intraocular pressure and pressure-lowering medication in patients after ab-interno trabeculectomy with the Trabectome.

Authors:  Markus Avar; Jens F Jordan; Matthias Neuburger; Diana Engesser; Jan Lübke; Alexandra Anton; Thomas Wecker
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-02-09       Impact factor: 3.117

2.  [Modern filtration surgery. An update].

Authors:  T Klink; F Grehn
Journal:  Ophthalmologe       Date:  2013-04       Impact factor: 1.059

3.  Absence of lymphatic vessels in non-functioning bleb capsules of glaucoma drainage devices.

Authors:  Robert Siggel; Falk Schroedl; Thomas Dietlein; Konrad R Koch; Christian Platzl; Alexandra Kaser-Eichberger; Claus Cursiefen; Ludwig M Heindl
Journal:  Histol Histopathol       Date:  2020-12-31       Impact factor: 2.303

4.  Functional evaluation of the filtering bleb by ultrasound biomicroscopy after trabeculectomy with mitomycin C.

Authors:  Ali Abbas El Salhy; Rabab Mohamed Elseht; Ahmed Fekry Al Maria; Saied Mohamed Abd El-Wahab Shalaby; Tarek Ragaee Hossein
Journal:  Int J Ophthalmol       Date:  2018-02-18       Impact factor: 1.779

5.  Evaluation of filtering blebs using the 'Wuerzburg bleb classification score' compared to clinical findings.

Authors:  Sandra Furrer; Marcel N Menke; Jens Funk; Marc Töteberg-Harms
Journal:  BMC Ophthalmol       Date:  2012-07-17       Impact factor: 2.209

6.  A comparative study of a modified filtering trabeculotomy and conventional trabeculectomy.

Authors:  Juliane Matlach; Matthias Hipp; Martin Wagner; Peter U Heuschmann; Thomas Klink; Franz Grehn
Journal:  Clin Ophthalmol       Date:  2015-03-13

7.  The DNA topoisomerase II inhibitor amsacrine as a novel candidate adjuvant in a model of glaucoma filtration surgery.

Authors:  Kotaro Yamamoto; Taiki Kokubun; Kota Sato; Takahiro Akaishi; Atsushi Shimazaki; Masatsugu Nakamura; Yukihiro Shiga; Satoru Tsuda; Kazuko Omodaka; Hideyuki Saya; Toru Nakazawa
Journal:  Sci Rep       Date:  2019-12-17       Impact factor: 4.379

8.  Outcome of Trabeculectomy with Collagen Matrix Implant versus Mitomycin C in Primary Glaucoma: A Comparative Study.

Authors:  Ashok K Sharma; Palak Gupta; Hans Raj Sharma
Journal:  Int J Appl Basic Med Res       Date:  2021-04-08

9.  Comparative study of trabeculectomy using single sutures versus releasable sutures.

Authors:  Juliane Matlach; Niels Hoffmann; Florentina J Freiberg; Franz Grehn; Thomas Klink
Journal:  Clin Ophthalmol       Date:  2012-07-06

10.  Postoperative subconjunctival bevacizumab injection as an adjunct to 5-fluorouracil in the management of scarring after trabeculectomy.

Authors:  Florentina Joyce Freiberg; Juliane Matlach; Franz Grehn; Sabine Karl; Thomas Klink
Journal:  Clin Ophthalmol       Date:  2013-06-20
  10 in total

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