Literature DB >> 29487814

Functional evaluation of the filtering bleb by ultrasound biomicroscopy after trabeculectomy with mitomycin C.

Ali Abbas El Salhy1, Rabab Mohamed Elseht2, Ahmed Fekry Al Maria2, Saied Mohamed Abd El-Wahab Shalaby2, Tarek Ragaee Hossein2.   

Abstract

AIM: To study the role of ultrasound biomicroscopy (UBM) in the assessment of the bleb function after trabeculectomy with mitomycin C (MMC).
METHODS: This was a cross-sectional study including all cases had undergone trabeculectomy with MMC 0.2 mg/mL for 3min. Participants were recruited from the follow-up cases at Department of Ophthalmology, Tanta University in the period from August 2015 to August 2016. Full history taking and ophthalmological examination were performed. Intraocular pressure (IOP) was measured using Goldmann applanation tonometry and the history of prescribed postoperative antiglaucoma medications was recorded. Accordingly, the trabeculectomy blebs were divided clinically into successful blebs when the IOP post-operative was ≤18 mm Hg without medications. Scanning examination of the filtering bleb using UBM examination was performed at the period from 2 to 36mo after trabeculectomy (13.6±9.7mo).
RESULTS: This study included 33 trabeculectomy filtering blebs of 25 patients (9 males and 16 females). The mean age of patients was 53.2±14.2y (range 25-71y). We had 20 eyes with complete success, 9 eyes with qualified success, and 4 eyes with failure after trabeculectomy with MMC. The blebs were classified into successful blebs (IOP ≤18 mm Hg without antiglaucoma medications), others were classified into qualified successful and failed blebs. There was a significant correlation between certain UBM findings (intra-bleb reflectivity, draining sub-scleral tract, bleb height, and intrableb fluid cysts) and cases with different grades of clinical functional success (P<0.01).
CONCLUSION: UBM is an objective tool in the functional assessment of the post-trabeculectomy filtering bleb through a significant correlation between certain UBM parameters and the different grades of clinical functional success.

Entities:  

Keywords:  bleb reflectivity; filtering bleb; sclerotomy site; sub-scleral tract; ultrasound biomicroscopy

Year:  2018        PMID: 29487814      PMCID: PMC5824079          DOI: 10.18240/ijo.2018.02.11

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  22 in total

1.  Relationship between formation of a filtering bleb and an intrascleral aqueous drainage route after trabeculectomy: evaluation using ultrasound biomicroscopy.

Authors:  K Jinza; S Saika; K Kin; Y Ohnishi
Journal:  Ophthalmic Res       Date:  2000 Sep-Oct       Impact factor: 2.892

Review 2.  The changing conceptual basis of trabeculectomy: a review of past and current surgical techniques.

Authors:  M Reza Razeghinejad; Scott J Fudemberg; George L Spaeth
Journal:  Surv Ophthalmol       Date:  2012 Jan-Feb       Impact factor: 6.048

3.  Bleb analysis by using anterior segment optical coherence tomography in two different methods of trabeculectomy.

Authors:  Teruhiko Hamanaka; Takayasu Omata; Shinichiro Sekimoto; Takakazu Sugiyama; Yasunori Fujikoshi
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-10-03       Impact factor: 4.799

4.  An ultrasound biomicroscopic study of filtering blebs after mitomycin C trabeculectomy.

Authors:  T Yamamoto; T Sakuma; Y Kitazawa
Journal:  Ophthalmology       Date:  1995-12       Impact factor: 12.079

Review 5.  Progress in anterior chamber angle imaging for glaucoma risk prediction - A review on clinical equipment, practice and research.

Authors:  Shinoj V K; Xun Jie Jeesmond Hong; Murukeshan V M; Baskaran M; Aung Tin
Journal:  Med Eng Phys       Date:  2016-10-24       Impact factor: 2.242

Review 6.  Wound modulation after filtration surgery.

Authors:  Leonard K Seibold; Mark B Sherwood; Malik Y Kahook
Journal:  Surv Ophthalmol       Date:  2012-11       Impact factor: 6.048

Review 7.  Modulation of wound healing in glaucoma surgery.

Authors:  Sarah Van de Velde; Tine Van Bergen; Evelien Vandewalle; Lieve Moons; Ingeborg Stalmans
Journal:  Prog Brain Res       Date:  2015-06-30       Impact factor: 2.453

8.  Intermediate-term outcome of variable dose mitomycin C filtering surgery.

Authors:  J C Cheung; M M Wright; S Murali; J E Pederson
Journal:  Ophthalmology       Date:  1997-01       Impact factor: 12.079

9.  Imaging of trabeculectomy blebs using anterior segment optical coherence tomography.

Authors:  Mandeep Singh; Paul T K Chew; David S Friedman; Winifred P Nolan; Jovina L See; Scott D Smith; Ce Zheng; Paul J Foster; Tin Aung
Journal:  Ophthalmology       Date:  2006-10-27       Impact factor: 12.079

10.  Morphologic classification of filtering blebs after glaucoma filtration surgery: the Indiana Bleb Appearance Grading Scale.

Authors:  Louis B Cantor; Anand Mantravadi; Darrell WuDunn; Kala Swamynathan; Arnold Cortes
Journal:  J Glaucoma       Date:  2003-06       Impact factor: 2.503

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  4 in total

1.  Quantitative analysis of functional filtering bleb size using Mask R-CNN.

Authors:  Tao Wang; Lei Zhong; Jing Yuan; Ting Wang; Shiyi Yin; Yi Sun; Xing Liu; Xun Liu; Shiqi Ling
Journal:  Ann Transl Med       Date:  2020-06

2.  Ultrasound Biomicroscopic Evaluation of Anterior Segment Parameters and Surgical Area Following Trabeculectomy Surgery.

Authors:  Cem Kesim; Nese Alagoz; Banu Solmaz; Cigdem Altan; Berna Basarir; Muhittin Taskapili
Journal:  Beyoglu Eye J       Date:  2020-02-19

3.  Prevalence of Plateau Iris in Primary Angle Closure Glaucoma: An Egyptian Hospital Based Ultrasound Biomicroscopy Study.

Authors:  Amira E Hamad; Ahmed F Elmaria; Tarek R Hussein; Said M Shalaby
Journal:  Clin Ophthalmol       Date:  2022-02-25

4.  Effects of Regorafenib, a Multi-Kinase Inhibitor, on Conjunctival Scarring in a Canine Filtration Surgery Model in Comparison with Mitomycin-C.

Authors:  Emika Nemoto; Shota Kojima; Tetsuya Sugiyama; Denan Jin; Shinji Takai; Michiko Maeda; Ryohsuke Kohmoto; Mari Ueki; Hidehiro Oku; Tsunehiko Ikeda
Journal:  Int J Mol Sci       Date:  2019-12-20       Impact factor: 5.923

  4 in total

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