Literature DB >> 20713719

Neuropeptide receptor positive allosteric modulation in epilepsy: galanin modulation revealed.

Daniel Hoyer1.   

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Year:  2010        PMID： 20713719      PMCID： PMC2930528          DOI： 10.1073/pnas.1010365107

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  18 in total

1.  Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling.

Authors:  Birgitte Holst; Erik Brandt; Anders Bach; Anders Heding; Thue W Schwartz
Journal:  Mol Endocrinol       Date:  2005-05-19

Review 2.  Allosteric modulation of G protein-coupled receptors.

Authors:  Lauren T May; Katie Leach; Patrick M Sexton; Arthur Christopoulos
Journal:  Annu Rev Pharmacol Toxicol       Date:  2007       Impact factor: 13.820

3.  M-15: high-affinity chimeric peptide that blocks the neuronal actions of galanin in the hippocampus, locus coeruleus, and spinal cord.

Authors:  T Bartfai; K Bedecs; T Land; U Langel; R Bertorelli; P Girotti; S Consolo; X J Xu; Z Wiesenfeld-Hallin; S Nilsson
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

4.  N-terminal galanin-(1-16) fragment is an agonist at the hippocampal galanin receptor.

Authors:  G Fisone; M Berthold; K Bedecs; A Undén; T Bartfai; R Bertorelli; S Consolo; J Crawley; B Martin; S Nilsson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

5.  Small-molecule agonists for the glucagon-like peptide 1 receptor.

Authors:  Lotte Bjerre Knudsen; Dan Kiel; Min Teng; Carsten Behrens; Dilip Bhumralkar; János T Kodra; Jens J Holst; Claus B Jeppesen; Michael D Johnson; Johannes Cornelis de Jong; Anker Steen Jorgensen; Tim Kercher; Jarek Kostrowicki; Peter Madsen; Preben H Olesen; Jacob S Petersen; Fritz Poulsen; Ulla G Sidelmann; Jeppe Sturis; Larry Truesdale; John May; Jesper Lau
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-09       Impact factor: 11.205

Review 6.  Galnon--a low-molecular weight ligand of the galanin receptors.

Authors:  Ulla Sollenberg; Tamas Bartfai; Ulo Langel
Journal:  Neuropeptides       Date:  2005-02-02       Impact factor: 3.286

7.  Neuropeptide Y gene therapy decreases chronic spontaneous seizures in a rat model of temporal lobe epilepsy.

Authors:  Francesco Noè; Allan-Hermann Pool; Jari Nissinen; Marco Gobbi; Ross Bland; Massimo Rizzi; Claudia Balducci; Francesco Ferraguti; Gunther Sperk; Matthew J During; Asla Pitkänen; Annamaria Vezzani
Journal:  Brain       Date:  2008-05-13       Impact factor: 13.501

8.  Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats.

Authors:  A Vezzani; G Civenni; M Rizzi; A Monno; S Messali; R Samanin
Journal:  Brain Res       Date:  1994-10-10       Impact factor: 3.252

Review 9.  Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.

Authors:  P Jeffrey Conn; Arthur Christopoulos; Craig W Lindsley
Journal:  Nat Rev Drug Discov       Date:  2009-01       Impact factor: 84.694

10.  Galanin receptor antagonists M40 and C7 block galanin-induced feeding.

Authors:  J N Crawley; J K Robinson; U Langel; T Bartfai
Journal:  Brain Res       Date:  1993-01-15       Impact factor: 3.252
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  1 in total

1.  Homology modeling, docking, and molecular dynamics simulation of the receptor GALR2 and its interactions with galanin and a positive allosteric modulator.

Authors:  Wen-Qi Hui; Qi Cheng; Tian-Yu Liu; Qin Ouyang
Journal:  J Mol Model       Date:  2016-03-28       Impact factor: 1.810
  1 in total

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