Literature DB >> 2070450

Structures and cytotoxic activity relationship of casearins, new clerodane diterpenes from Casearia sylvestris Sw.

H Morita1, M Nakayama, H Kojima, K Takeya, H Itokawa, E P Schenkel, M Motidome.   

Abstract

Casearins G-R, new cytotoxic clerodane diterpenes have been isolated from the leaves of Casearia sylvestris Sw. (Flacourtiaceae). Their structures have been elucidated by spectroscopic methods and chemical conversions, and their structure-activity relationships have been discussed.

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Year:  1991        PMID： 2070450     DOI： 10.1248/cpb.39.693

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  6 in total

Review 1.  Clerodane diterpenes: sources, structures, and biological activities.

Authors:  Rongtao Li; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Nat Prod Rep       Date:  2016-07-18       Impact factor: 13.423

2.  Laevigatbenzoate from Croton laevigatus Vahl.

Authors:  Guo-An Zou; Hong-Wu Zhang; Haji Akber Aisa; Jun-Shan Yang; Chao-Zhong Peng; Zhong-Mei Zou
Journal:  J Nat Med       Date:  2011-01-21       Impact factor: 2.343

3.  Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers.

Authors:  Emily L Whitson; Cheryl L Thomas; Curtis J Henrich; Thomas J Sayers; James B McMahon; Tawnya C McKee
Journal:  J Nat Prod       Date:  2010-11-10       Impact factor: 4.050

4.  Chemopreventive potential of Epoxy clerodane diterpene from Tinospora cordifolia against diethylnitrosamine-induced hepatocellular carcinoma.

Authors:  Muniyappan Dhanasekaran; Arul-Albert Baskar; Savarimuthu Ignacimuthu; Paul Agastian; Veeramuthu Duraipandiyan
Journal:  Invest New Drugs       Date:  2008-10-14       Impact factor: 3.850

5.  Evaluation of the Effects of Some Brazilian Medicinal Plants on the Production of TNF- α and CCL2 by THP-1 Cells.

Authors:  Grasielle S Gusman; Priscilla R V Campana; Luciano C Castro; Rachel O Castilho; Mauro M Teixeira; Fernão C Braga
Journal:  Evid Based Complement Alternat Med       Date:  2015-03-23       Impact factor: 2.629

6.  Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans.

Authors:  Sabrina M Ribeiro; Érick D O Fratucelli; Paula C P Bueno; Marlene Kelly V de Castro; Amanda Alcalá Francisco; Alberto José Cavalheiro; Marlise I Klein
Journal:  BMC Complement Altern Med       Date:  2019-11-12       Impact factor: 3.659
  6 in total

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