Literature DB >> 20703255

Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.

E L Davenport, A Zeisig, L I Aronson, H E Moore, S Hockley, D Gonzalez, E M Smith, M V Powers, S Y Sharp, P Workman, G J Morgan, F E Davies.   

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Year:  2010        PMID： 20703255     DOI： 10.1038/leu.2010.168

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  37 in total

1.  The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis.

Authors:  Gaoxiang Wang; Pan Zhou; Xing Chen; Lei Zhao; Jiaqi Tan; Yang Yang; Yong Fang; Jianfeng Zhou
Journal:  Cancer Biol Ther       Date:  2017-07-18       Impact factor: 4.742

2.  The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways.

Authors:  Wonkyoung Cho; Xiongjie Jin; Junfeng Pang; Yan Wang; Nahid F Mivechi; Demetrius Moskophidis
Journal:  Mol Cell Biol       Date:  2019-04-16       Impact factor: 4.272

3.  Understanding of the Hsp90 molecular chaperone reaches new heights.

Authors:  Cara K Vaughan; Len Neckers; Peter W Piper
Journal:  Nat Struct Mol Biol       Date:  2010-12       Impact factor: 15.369

Review 4.  Novel therapeutic strategies for multiple myeloma.

Authors:  Naoya Mimura; Teru Hideshima; Kenneth C Anderson
Journal:  Exp Hematol       Date:  2015-06-26       Impact factor: 3.084

5.  Bioactive metabolites from Chaetomium aureum: structure elucidation and inhibition of the Hsp90 machine chaperoning activity.

Authors:  Fatima Zahra Kabbaj; Su Lu; My El Abbés Faouzi; Bouchra Meddah; Peter Proksch; Yahya Cherrah; Hans-Josef Altenbach; Amal H Aly; Ahmed Chadli; Abdessamad Debbab
Journal:  Bioorg Med Chem       Date:  2014-11-20       Impact factor: 3.641

6.  The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma.

Authors:  Manik Chatterjee; Mindaugas Andrulis; Thorsten Stühmer; Elisabeth Müller; Claudia Hofmann; Torsten Steinbrunn; Tanja Heimberger; Heike Schraud; Stefanie Kressmann; Hermann Einsele; Ralf C Bargou
Journal:  Haematologica       Date:  2012-10-12       Impact factor: 9.941

7.  The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors.

Authors:  Sudhakar Voruganti; Jeff C Lacroix; Chelsea N Rogers; Janet Rogers; Robert L Matts; Steven D Hartson
Journal:  J Proteome Res       Date:  2013-06-27       Impact factor: 4.466

Review 8.  The HSP70 family and cancer.

Authors:  Maureen E Murphy
Journal:  Carcinogenesis       Date:  2013-04-04       Impact factor: 4.944

9.  Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway.

Authors:  Akira Wagatsuma; Yuzo Takayama; Takayuki Hoshino; Masataka Shiozuka; Shigeru Yamada; Ryoichi Matsuda; Kunihiko Mabuchi
Journal:  Mol Cell Biochem       Date:  2017-12-16       Impact factor: 3.396

10.  Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades.

Authors:  Sharan R Srinivasan; Laura C Cesa; Xiaokai Li; Olivier Julien; Min Zhuang; Hao Shao; Jooho Chung; Ivan Maillard; James A Wells; Colin S Duckett; Jason E Gestwicki
Journal:  Mol Cancer Res       Date:  2017-09-28       Impact factor: 5.852
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