Literature DB >> 21127511

Understanding of the Hsp90 molecular chaperone reaches new heights.

Cara K Vaughan1, Len Neckers, Peter W Piper.   

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Year:  2010        PMID： 21127511      PMCID： PMC7560985          DOI： 10.1038/nsmb1210-1400

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


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  34 in total

Review 1.  Hsp90 isoforms: functions, expression and clinical importance.

Authors:  Amere Subbarao Sreedhar; Eva Kalmár; Péter Csermely; Yu-Fei Shen
Journal:  FEBS Lett       Date:  2004-03-26       Impact factor: 4.124

2.  Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance.

Authors:  Ron Geller; Marco Vignuzzi; Raul Andino; Judith Frydman
Journal:  Genes Dev       Date:  2007-01-15       Impact factor: 11.361

Review 3.  Molecular recognition and drug-lead identification: what can molecular simulations tell us?

Authors:  Giulia Morra; Alessandro Genoni; Marco A C Neves; Kenneth M Merz; Giorgio Colombo
Journal:  Curr Med Chem       Date:  2010       Impact factor: 4.530

Review 4.  Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection.

Authors:  R I Morimoto; M G Santoro
Journal:  Nat Biotechnol       Date:  1998-09       Impact factor: 54.908

5.  Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi and evaluation of its inhibitor as a candidate drug.

Authors:  Rani Pallavi; Nainita Roy; Rishi Kumar Nageshan; Pinaki Talukdar; Soundara Raghavan Pavithra; Raghunath Reddy; S Venketesh; Rajender Kumar; Ashok Kumar Gupta; Raj Kumar Singh; Suresh Chandra Yadav; Utpal Tatu
Journal:  J Biol Chem       Date:  2010-09-13       Impact factor: 5.157

Review 6.  Targeting the dynamic HSP90 complex in cancer.

Authors:  Jane Trepel; Mehdi Mollapour; Giuseppe Giaccone; Len Neckers
Journal:  Nat Rev Cancer       Date:  2010-08       Impact factor: 60.716

Review 7.  Update on Hsp90 inhibitors in clinical trial.

Authors:  Y S Kim; S V Alarcon; S Lee; M-J Lee; G Giaccone; L Neckers; J B Trepel
Journal:  Curr Top Med Chem       Date:  2009       Impact factor: 3.295

8.  Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line.

Authors:  Yuanming Lu; Sabah Ansar; Mary L Michaelis; Brian S J Blagg
Journal:  Bioorg Med Chem       Date:  2008-12-25       Impact factor: 3.641

9.  The chaperone activity of GRP94 toward insulin-like growth factor II is necessary for the stress response to serum deprivation.

Authors:  Olga Ostrovsky; Noreen T Ahmed; Yair Argon
Journal:  Mol Biol Cell       Date:  2009-01-21       Impact factor: 4.138

10.  Structural basis for assembly of Hsp90-Sgt1-CHORD protein complexes: implications for chaperoning of NLR innate immunity receptors.

Authors:  Minghao Zhang; Yasuhiro Kadota; Chrisostomos Prodromou; Ken Shirasu; Laurence H Pearl
Journal:  Mol Cell       Date:  2010-07-30       Impact factor: 17.970
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  15 in total

1.  Novobiocin analogues with second-generation noviose surrogates.

Authors:  Huiping Zhao; Brian S J Blagg
Journal:  Bioorg Med Chem Lett       Date:  2012-11-22       Impact factor: 2.823

2.  Hsp90 interacts with inducible NO synthase client protein in its heme-free state and then drives heme insertion by an ATP-dependent process.

Authors:  Arnab Ghosh; Mamta Chawla-Sarkar; Dennis J Stuehr
Journal:  FASEB J       Date:  2011-02-25       Impact factor: 5.191

3.  The protein chaperone HSP90 can facilitate the divergence of gene duplicates.

Authors:  Jennifer Lachowiec; Tzitziki Lemus; James H Thomas; Patrick J M Murphy; Jennifer L Nemhauser; Christine Queitsch
Journal:  Genetics       Date:  2013-02-14       Impact factor: 4.562

4.  A highly selective Hsp90 affinity chromatography resin with a cleavable linker.

Authors:  Philip F Hughes; Jared J Barrott; David A Carlson; David R Loiselle; Brittany L Speer; Khaldon Bodoor; Lauretta A Rund; Timothy A J Haystead
Journal:  Bioorg Med Chem       Date:  2012-03-29       Impact factor: 3.641

5.  Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.

Authors:  John Labbadia; Helen Cunliffe; Andreas Weiss; Elena Katsyuba; Kirupa Sathasivam; Tamara Seredenina; Ben Woodman; Saliha Moussaoui; Stefan Frentzel; Ruth Luthi-Carter; Paolo Paganetti; Gillian P Bates
Journal:  J Clin Invest       Date:  2011-07-25       Impact factor: 14.808

6.  Triazole Containing Novobiocin and Biphenyl Amides as Hsp90 C-Terminal Inhibitors.

Authors:  Jinbo Zhao; Huiping Zhao; Jessica A Hall; Douglas Brown; Eileen Brandes; Joseph Bazzill; Patrick T Grogan; Chitra Subramanian; George Vielhauer; Mark S Cohen; Brian S J Blagg
Journal:  Medchemcomm       Date:  2014-09-01       Impact factor: 3.597

7.  HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study.

Authors:  Takuya Osada; Erika J Crosby; Kensuke Kaneko; Joshua C Snyder; Joshua D Ginzel; Chaitanya R Acharya; Xiao-Yi Yang; Thomas J Polascik; Ivan Spasojevic; Rendon C Nelson; Amy Hobeika; Zachary C Hartman; Leonard M Neckers; Andre Rogatko; Philip F Hughes; Jiaoti Huang; Michael A Morse; Timothy Haystead; H Kim Lyerly
Journal:  Mol Cancer Ther       Date:  2021-10-21       Impact factor: 6.261

Review 8.  Protein homeostasis as a therapeutic target for diseases of protein conformation.

Authors:  Barbara Calamini; Richard I Morimoto
Journal:  Curr Top Med Chem       Date:  2012       Impact factor: 3.295

9.  Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.

Authors:  Jared J Barrott; Philip F Hughes; Takuya Osada; Xiao-Yi Yang; Zachary C Hartman; David R Loiselle; Neil L Spector; Len Neckers; Narasimhan Rajaram; Fangyao Hu; Nimmi Ramanujam; Ganesan Vaidyanathan; Michael R Zalutsky; H Kim Lyerly; Timothy A Haystead
Journal:  Chem Biol       Date:  2013-09-12

10.  The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition.

Authors:  Sanket J Mishra; Weiya Liu; Kristin Beebe; Monimoy Banerjee; Caitlin N Kent; Vitumbiko Munthali; John Koren; John A Taylor; Leonard M Neckers; Jeffrey Holzbeierlein; Brian S J Blagg
Journal:  J Med Chem       Date:  2021-01-11       Impact factor: 7.446
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