Literature DB >> 20701621

Benefits of dental implants installed during ablative tumour surgery in oral cancer patients: a prospective 5-year clinical trial.

Anke Korfage1, Pieter J Schoen, Gerry M Raghoebar, Jan L N Roodenburg, Arjan Vissink, Harry Reintsema.   

Abstract

OBJECTIVE: This prospective study assessed treatment outcome and patient satisfaction of oral cancer patients with a mandibular overdenture on implants up to 5 years after treatment.
MATERIALS AND METHODS: At baseline, 50 consecutive edentulous oral cancer patients, in whom prosthetic problems were expected after oncological treatment, were evaluated by standardized questionnaires and clinical assessments. All implants were installed during ablative tumour surgery in native bone in the interforaminal area. About two-thirds of the patients (n=31) had radiotherapy post-surgery (dose >40 Gy in the interforaminal area).
RESULTS: At the 5-year evaluation, 26 patients had passed away and four patients had to be excluded from the analyses, because superstructures were not present, due to persistent local irritation (n=2), loss of three implants (n=1) and the impossibility of making an overdenture related to tumour and oncological surgery-driven anatomical limitations (n=1). In the remaining 20 patients, the prosthesis was still in function (76 implants). During the 5-year follow-up, total 14 implants were lost, 13 in irradiated bone (survival rate 89.4%, dose >40 Gy) and one in non-irradiated bone (survival rate 98.6%). Peri-implant tissues had a healthy appearance and remained healthy over time. Patients were satisfied with their dentures.
CONCLUSIONS: It was concluded that oral cancer patients can benefit from implants installed during ablative surgery, with a high survival rate of the implants, a high percentage of rehabilitated patients and a high denture satisfaction up to 5 years after treatment.

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Year:  2010        PMID: 20701621     DOI: 10.1111/j.1600-0501.2010.01930.x

Source DB:  PubMed          Journal:  Clin Oral Implants Res        ISSN: 0905-7161            Impact factor:   5.977


  21 in total

Review 1.  Oral rehabilitation with dental implants in irradiated patients: a meta-analysis on implant survival.

Authors:  E Schiegnitz; B Al-Nawas; P W Kämmerer; K A Grötz
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2.  Dental implants in irradiated patients: which factors influence implant survival?

Authors:  Anke Korfage; Pieter U Dijkstra; Jan L N Roodenburg; Harry Reintsema; Gerry M Raghoebar; Arjan Vissink
Journal:  Clin Oral Investig       Date:  2015-03-05       Impact factor: 3.573

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10.  Clinical long-term and patient-reported outcomes of dental implants in oral cancer patients.

Authors:  Eik Schiegnitz; Lena Katharina Müller; Keyvan Sagheb; Lisa Theis; Vahide Cagiran; Peer W Kämmerer; Joachim Wegener; Wilfried Wagner; Bilal Al-Nawas
Journal:  Int J Implant Dent       Date:  2021-07-13
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