Levente Kriston1, Alessa von Wolff. 1. Department of Medical Psychology, University Medical Center Hamburg-Eppendorf Martinistr. 52, D-20246 Hamburg, Germany. l.kriston@uke.uni-hamburg.de
Abstract
BACKGROUND: The Hamilton Rating Scale for Depression (HRSD) is one of the most frequently used instruments in antidepressant trials. METHODS: We examined different recommendations for classification of subjects according to depression severity by the HRSD. RESULTS: Several differences between recommendations were identified leading to the conclusion that a consensus on interpretation is largely missing. LIMITATIONS: Brief narrative review. CONCLUSIONS: Widely accepted standards for the interpretation of scores on the HRSD are needed.
BACKGROUND: The Hamilton Rating Scale for Depression (HRSD) is one of the most frequently used instruments in antidepressant trials. METHODS: We examined different recommendations for classification of subjects according to depression severity by the HRSD. RESULTS: Several differences between recommendations were identified leading to the conclusion that a consensus on interpretation is largely missing. LIMITATIONS: Brief narrative review. CONCLUSIONS: Widely accepted standards for the interpretation of scores on the HRSD are needed.
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