Literature DB >> 2069383

Lack of effective bactericidal activity of new quinolones against Brucella spp.

J A García-Rodriguez1, J E García Sánchez, I Trujillano.   

Abstract

The in vitro activities of six fluoroquinolones against 43 Brucella spp. were compared by testing three different inocula at two medium pH values. The influence of the test conditions was moderate. The activities of all quinolones were lower at pH 5 and with a high inoculum size. Results indicate the lack of effective bactericidal activity of quinolones against most strains of Brucella spp., particularly B. abortus.

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Year:  1991        PMID： 2069383      PMCID： PMC245093          DOI： 10.1128/AAC.35.4.756

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

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Authors:  S M Qadri; M Akhtar; Y Ueno; M B al-Sibai
Journal:  Drugs Exp Clin Res       Date:  1989

2.  Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

Authors:  S Ohkuma; B Poole
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

3.  The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

Authors:  J S Wolfson; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191

4.  In vitro activity of ciprofloxacin against Brucella melitensis.

Authors:  M Gobernado; E Cantón; M Santos
Journal:  Eur J Clin Microbiol       Date:  1984-08       Impact factor: 3.267

5.  Comparison of three different regimens in the treatment of acute brucellosis: a multicenter multinational study.

Authors:  G Acocella; A Bertrand; J Beytout; J B Durrande; J A Garcia Rodriguez; J Kosmidis; M Micoud; M Rey; M Rodriguez Zapata; J Roux
Journal:  J Antimicrob Chemother       Date:  1989-03       Impact factor: 5.790

6.  Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis.

Authors:  M Y Khan; M Dizon; F W Kiel
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

7.  Effect of ciprofloxacin on intracellular organisms: in-vitro and in-vivo studies.

Authors:  C S Easmon; J P Crane; A Blowers
Journal:  J Antimicrob Chemother       Date:  1986-11       Impact factor: 5.790

8.  Uptake of ciprofloxacin by human neutrophils.

Authors:  C S Easmon; J P Crane
Journal:  J Antimicrob Chemother       Date:  1985-07       Impact factor: 5.790

9.  Uptake of ciprofloxacin by macrophages.

Authors:  C S Easmon; J P Crane
Journal:  J Clin Pathol       Date:  1985-04       Impact factor: 3.411

10.  High-performance liquid chromatography measurement of antimicrobial concentrations in polymorphonuclear leukocytes.

Authors:  H Koga
Journal:  Antimicrob Agents Chemother       Date:  1987-12       Impact factor: 5.191
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  22 in total

1.  Comparison of E test to microdilution for determining in vitro activities of antibiotics against Brucella melitensis.

Authors:  D Gür; S Kocagöz; M Akova; S Unal
Journal:  Antimicrob Agents Chemother       Date:  1999-09       Impact factor: 5.191

2.  In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs.

Authors:  M Akova; D Gür; D M Livermore; T Kocagöz; H E Akalin
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

3.  Functional characterization of Brucella melitensis NorMI, an efflux pump belonging to the multidrug and toxic compound extrusion family.

Authors:  Martine Braibant; Laurence Guilloteau; Michel S Zygmunt
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

Review 4.  Quinolones for treatment of human brucellosis: critical review of the evidence from microbiological and clinical studies.

Authors:  Matthew E Falagas; Ioannis A Bliziotis
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

5.  In vitro activity of nonsteroidal anti-inflammatory agents, phenotiazines, and antidepressants against Brucella species.

Authors:  S Muñoz-Criado; J L Muñoz-Bellido; J A García-Rodríguez
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1996-05       Impact factor: 3.267

6.  In vitro activities of six new fluoroquinolones against Brucella melitensis.

Authors:  I Trujillano-Martín; E García-Sánchez; I M Martínez; M J Fresnadillo; J E García-Sánchez; J A García-Rodríguez
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

Review 7.  Lomefloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  A N Wadworth; K L Goa
Journal:  Drugs       Date:  1991-12       Impact factor: 9.546

Review 8.  Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use.

Authors:  P A Todd; D Faulds
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

Review 9.  Quinolones in intracellular infections.

Authors:  J C Pechère
Journal:  Drugs       Date:  1993       Impact factor: 9.546

10.  In vitro activities of new macrolides and rifapentine against Brucella spp.

Authors:  J A García-Rodríguez; J L Muñoz Bellido; M J Fresnadillo; I Trujillano
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191
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