Literature DB >> 20693620

Alzheimer Center Reina Sofia Foundation: fighting the disease and providing overall solutions.

Pablo Martínez-Martín1, Jesús Avila.   

Abstract

As the impact of Alzheimer's disease (AD) on society expands, the reaction aimed at neutralizing its effects also increases. In Spain, an initiative arisen from the highest institution of the State has launched a crusade for fighting the disease from a multidisciplinary stance. In 2002, the "Alzheimer Project" of the Reina Sofia Foundation was announced and in 2007, the Alzheimer Center Reina Sofia Foundation was inaugurated. This resource includes a long-term inpatient care facility, a day-care center, premises for education and training, and a research unit. This way, patients and investigators share the space in a clear expression of "translational research". The Research Unit is managed by the CIEN Foundation, Carlos III Institute of Health, an entity depending on the Ministry of Science and Innovation, and financed in part by the Reina Sofia Foundation. It includes clinical and social research, laboratory, neuroimaging (MRI 3T), and biobank facilities. The connection of the Unit with other research centers and laboratories (both in Spain and outside), universities, and associations of AD patients' relatives is tight and facilitates a dynamic collaboration. The involvement of all social strata in the Alzheimer Project makes evident the unitary effort that Spain is carrying out in the fight against neurodegenerative diseases and, particularly, AD.

Entities:  

Mesh:

Year:  2010        PMID: 20693620     DOI: 10.3233/JAD-2010-101149

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN: 1387-2877            Impact factor:   4.472


  8 in total

1.  Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia.

Authors:  Julia Terreros-Roncal; Miguel Flor-García; Elena P Moreno-Jiménez; Noemí Pallas-Bazarra; Alberto Rábano; Nirnath Sah; Henriette van Praag; Damiana Giacomini; Alejandro F Schinder; Jesús Ávila; Maria Llorens-Martín
Journal:  J Neurosci       Date:  2019-05-27       Impact factor: 6.167

2.  Validation of the multimodal assessment of capacities in severe dementia: a novel cognitive and functional scale for use in severe dementia.

Authors:  Sloane Heller; Carolina Mendoza Rebolledo; Carmen Rodríguez Blázquez; Laura Carrasco Chillón; Almudena Pérez Muñoz; Irene Rodríguez Pérez; Pablo Martínez-Martín
Journal:  J Neurol       Date:  2015-03-06       Impact factor: 4.849

3.  Alzheimer's disease and disseminated mycoses.

Authors:  R Alonso; D Pisa; A Rábano; L Carrasco
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-01-23       Impact factor: 3.267

4.  Evidences for Adult Hippocampal Neurogenesis in Humans.

Authors:  Elena P Moreno-Jiménez; Julia Terreros-Roncal; Miguel Flor-García; Alberto Rábano; María Llorens-Martín
Journal:  J Neurosci       Date:  2021-03-24       Impact factor: 6.167

5.  Impact of neurodegenerative diseases on human adult hippocampal neurogenesis.

Authors:  J Terreros-Roncal; E P Moreno-Jiménez; M Flor-García; C B Rodríguez-Moreno; M F Trinchero; F Cafini; A Rábano; M Llorens-Martín
Journal:  Science       Date:  2021-10-21       Impact factor: 63.714

6.  Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer's disease.

Authors:  Almudena Fuster-Matanzo; Jerónimo Jurado-Arjona; Stefano Benvegnù; Esther García; Patricia Martín-Maestro; Raquel Gómez-Sintes; Félix Hernández; Jesús Ávila
Journal:  Cell Mol Life Sci       Date:  2016-11-10       Impact factor: 9.261

7.  Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment.

Authors:  Aidan Kenny; Hazel McArdle; Miguel Calero; Alberto Rabano; Stephen F Madden; Kellie Adamson; Robert Forster; Elaine Spain; Jochen H M Prehn; David C Henshall; Miguel Medina; Eva M Jimenez-Mateos; Tobias Engel
Journal:  Biomolecules       Date:  2019-11-13

8.  Progression of Alzheimer's disease parallels unusual structural plasticity of human dentate granule cells.

Authors:  B Márquez-Valadez; A Rábano; M Llorens-Martín
Journal:  Acta Neuropathol Commun       Date:  2022-08-29       Impact factor: 7.578

  8 in total

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