BACKGROUND AND PURPOSE: Although peripheral artery disease (PAD) has a particularly poor prognosis compared with vascular disease in other territories, little attention is paid to its epidemiology, treatment, and prevention. Despite the high prevalence of PAD in patients with stroke, and of stroke in patients with PAD, PAD is omitted from all guidelines for treatment, prevention, and rehabilitation of stroke, although coronary artery disease risk is considered. Therefore, routine PAD screening is seldom undertaken and so disease is probably often missed. Summary of Review- This review evaluates epidemiology of PAD in patients with stroke and of stroke in patients with PAD. The role of the ankle-brachial pressure index; imaging and novel markers in risk prediction of PAD in patients with stroke; and treatment and prevention of PAD are reviewed. CONCLUSIONS: In both primary and secondary prevention settings, PAD indicates a high risk of future events. Data on which additional preventive measures are beneficial in this patient group are lacking, but the presence of PAD does have implications for current management in both primary and secondary prevention of stroke.
BACKGROUND AND PURPOSE: Although peripheral artery disease (PAD) has a particularly poor prognosis compared with vascular disease in other territories, little attention is paid to its epidemiology, treatment, and prevention. Despite the high prevalence of PAD in patients with stroke, and of stroke in patients with PAD, PAD is omitted from all guidelines for treatment, prevention, and rehabilitation of stroke, although coronary artery disease risk is considered. Therefore, routine PAD screening is seldom undertaken and so disease is probably often missed. Summary of Review- This review evaluates epidemiology of PAD in patients with stroke and of stroke in patients with PAD. The role of the ankle-brachial pressure index; imaging and novel markers in risk prediction of PAD in patients with stroke; and treatment and prevention of PAD are reviewed. CONCLUSIONS: In both primary and secondary prevention settings, PAD indicates a high risk of future events. Data on which additional preventive measures are beneficial in this patient group are lacking, but the presence of PAD does have implications for current management in both primary and secondary prevention of stroke.
Authors: Alexander C Fanaroff; Pratik Manandhar; David R Holmes; David J Cohen; J Kevin Harrison; G Chad Hughes; Vinod H Thourani; Michael J Mack; Matthew W Sherwood; W Schuyler Jones; Sreekanth Vemulapalli Journal: Circ Cardiovasc Interv Date: 2017-10 Impact factor: 6.546
Authors: Alexander A Sidyakin; Anna L Kaysheva; Artur T Kopylov; Alexander V Lobanov; Sergei G Morozov Journal: J Mol Neurosci Date: 2018-04-26 Impact factor: 3.444
Authors: Kristian Barlinn; Stanislava Kolieskova; Reza Bavarsad Shahripour; Jessica Kepplinger; Amelia K Boehme; Timo Siepmann; Volker Puetz; Ulf Bodechtel; William D Jordan; Andrei V Alexandrov Journal: J Stroke Cerebrovasc Dis Date: 2014-11-06 Impact factor: 2.136
Authors: Razvan Anghel; Cristina Andreea Adam; Ovidiu Mitu; Dragos Traian Marius Marcu; Viviana Onofrei; Mihai Roca; Alexandru Dan Costache; Radu Stefan Miftode; Grigore Tinica; Florin Mitu Journal: Diagnostics (Basel) Date: 2022-06-20