J Ryan Martin1, Jason G Bromer, Denny Sakkas, Pasquale Patrizio. 1. Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, Yale Fertility Center, New Haven, Connecticut 06510, USA
Abstract
OBJECTIVE: To compare the impact of mandated IVF insurance coverage on ET practices and resulting multiple pregnancy rates. DESIGN: Retrospective analysis of all fresh, nondonor IVF cycles performed in the United States in 2006. SETTING: United States. PATIENT(S): A total of 91,753 fresh, nondonor IVF cycles in the United States. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Pregnancy rate, live-birth rate, embryos transferred, multiple pregnancy rate. RESULT(S): Overall, nonmandated states had a significantly higher pregnancy rate (38.8% vs. 35%) and live-birth rate (32.2% vs. 29.1%) than mandated states. Nonmandated states also had a significantly higher twin rate (28.1% vs. 26%) and triplet rate (3.9% vs. 3.4%). The average number of embryos transferred was also significantly higher in nonmandated states (2.6 vs. 2.2). These findings were more pronounced in the <35 and 35-37 age groups. CONCLUSION(S): In the last 8 years, despite a reduction in the average number of embryos transferred and multiple pregnancy rates, there is a continued association between mandated IVF coverage, the transfer of fewer embryos, and lower rates of multiple pregnancies and births, particularly in the younger age groups.
OBJECTIVE: To compare the impact of mandated IVF insurance coverage on ET practices and resulting multiple pregnancy rates. DESIGN: Retrospective analysis of all fresh, nondonor IVF cycles performed in the United States in 2006. SETTING: United States. PATIENT(S): A total of 91,753 fresh, nondonor IVF cycles in the United States. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Pregnancy rate, live-birth rate, embryos transferred, multiple pregnancy rate. RESULT(S): Overall, nonmandated states had a significantly higher pregnancy rate (38.8% vs. 35%) and live-birth rate (32.2% vs. 29.1%) than mandated states. Nonmandated states also had a significantly higher twin rate (28.1% vs. 26%) and triplet rate (3.9% vs. 3.4%). The average number of embryos transferred was also significantly higher in nonmandated states (2.6 vs. 2.2). These findings were more pronounced in the <35 and 35-37 age groups. CONCLUSION(S): In the last 8 years, despite a reduction in the average number of embryos transferred and multiple pregnancy rates, there is a continued association between mandated IVF coverage, the transfer of fewer embryos, and lower rates of multiple pregnancies and births, particularly in the younger age groups.
Authors: Barbara Luke; Morton B Brown; Ethan Wantman; Judy E Stern; Valerie L Baker; Eric Widra; Charles C Coddington; William E Gibbons; Bradley J Van Voorhis; G David Ball Journal: Am J Obstet Gynecol Date: 2015-02-13 Impact factor: 8.661
Authors: Sheree L Boulet; Sara Crawford; Yujia Zhang; Saswati Sunderam; Bruce Cohen; Dana Bernson; Patricia McKane; Marie A Bailey; Denise J Jamieson; Dmitry M Kissin Journal: Fertil Steril Date: 2015-06-11 Impact factor: 7.329
Authors: April L Dawson; Sarah C Tinker; Denise J Jamieson; Charlotte A Hobbs; Sonja A Rasmussen; Jennita Reefhuis Journal: Birth Defects Res A Clin Mol Teratol Date: 2014-10-31